Protein Alignment GstE5 and GSTA4

DIOPT Version :10

• Sequence 1: NP_611327.1
• Gene: GstE5 / 37110
• FlyBaseID: FBgn0063495
• Length: 222
• Species: Drosophila melanogaster
• Sequence 2: NP_001503.1
• Gene: GSTA4 / 2941
• HGNCID: 4629
• Length: 222
• Species: Homo sapiens
• Alignment Length: 207
• Identity: 45/207 - (21%)
• Similarity: 94/207 - (45%)
• Gaps: 31/207 - (14%)

  Fly    15 VRAVKLTLAALQLPYEFVNVNISGQEQLSEEYLKKNPEH----TVPTLEDDGNYIWDSHAIIAYL 75
            :.:|:..|||..:  ||....:..:|||   |..::..|    .||.:|.||..:..:.:|:.|:
Human    16 MESVRWVLAAAGV--EFDEEFLETKEQL---YKLQDGNHLLFQQVPMVEIDGMKLVQTRSILHYI 75

  Fly    76 VSKYADSDALYPRDLLQRAVVDQRLHFETGVVFANGIKAITKPLFFNGLNRIPKERYD------- 133
                ||...|:.::|.:|.::|         ::..|...:.:.|..:...:...::.:
Human    76 ----ADKHNLFGKNLKERTLID---------MYVEGTLDLLELLIMHPFLKPDDQQKEVVNMAQK 127

  Fly   134 AIVEIYDFVETFLAGH--DYIAGDQLTIADFSLISSITSLVAFVEIDRLKYPRIIEWVRRLEKLP 196
            ||:..:...|..|.||  .::.|:||::||..|:.:|.:|...:......:|.:.|:..:|..:|
Human   128 AIIRYFPVFEKILRGHGQSFLVGNQLSLADVILLQTILALEEKIPNILSAFPFLQEYTVKLSNIP 192

  Fly   197 YYEEANAKGARE 208
            ..:.....|:::
Human   193 TIKRFLEPGSKK 204

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GstE5	NP_611327.1	GstA	4..210	CDD:440390	45/207 (22%)
GSTA4	NP_001503.1	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold	4..82	CDD:469754	20/74 (27%)
		GST_C_Alpha	86..220	CDD:198317	24/128 (19%)