Protein Alignment GstE5 and GSTT4

DIOPT Version :10

• Sequence 1: NP_611327.1
• Gene: GstE5 / 37110
• FlyBaseID: FBgn0063495
• Length: 222
• Species: Drosophila melanogaster
• Sequence 2: NP_001345593.1
• Gene: GSTT4 / 25774
• HGNCID: 26930
• Length: 241
• Species: Homo sapiens
• Alignment Length: 214
• Identity: 59/214 - (27%)
• Similarity: 92/214 - (42%)
• Gaps: 41/214 - (19%)

  Fly     4 LTLYGVNPSPPVRAVKLTLAALQLPYEFVNVNISGQEQLSEEYLKKNPEHTVPTLEDDGNYIWDS 68
            |.||....|.|.|||.:......:.:.|..|::......|:.|:..||...:|:|:|....:.:|
Human     3 LELYMDLLSAPCRAVYIFSKKHDIQFNFQFVDLLKGHHHSKGYIDINPLRKLPSLKDGKFILSES 67

  Fly    69 HAIIAYLVSKYADSDALYPRDLLQRAVVDQRLHFETGVVFANGIKAIT--KPLFFNGLNRIPK-- 129
            .||:.||..||:......|.|...||.||:.:.:: ...|...:|.|.  |.|       |||
Human    68 AAILYYLCRKYSAPSHWCPPDPHARARVDEFVAWQ-HTAFQLPMKKIVWLKLL-------IPKIT 124

  Fly   130 ------ERYDAIVE-----IYDFVETFLAGHDYIAGDQLTIADFSLISSITSLVAFVEIDR---- 179
                  |:.:..||     :..|.|.||....:|.|:|:::||         |||.||:.:
Human   125 GEEVSAEKMEHAVEEVKNSLQLFEEYFLQDKMFITGNQISLAD---------LVAVVEMMQPMAA 180

  Fly   180 -----LKYPRIIEWVRRLE 193
                 |...::.||..::|
Human   181 NYNVFLNSSKLAEWRMQVE 199

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GstE5	NP_611327.1	GstA	4..210	CDD:440390	59/214 (28%)
GSTT4	NP_001345593.1	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold	3..78	CDD:469754	22/74 (30%)
		GST_C_Theta	91..217	CDD:198292	33/126 (26%)