DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstE5 and clic6

DIOPT Version :9

Sequence 1:	NP_611327.1	Gene:	GstE5 / 37110	FlyBaseID:	FBgn0063495	Length:	222	Species:	Drosophila melanogaster
Sequence 2:	XP_002941923.2	Gene:	clic6 / 100486547	XenbaseID:	XB-GENE-6039572	Length:	831	Species:	Xenopus tropicalis

Alignment Length:	157	Identity:	33/157 - (21%)
Similarity:	64/157 - (40%)	Gaps:	41/157 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 VNVNISGQEQLSEE------YLKKNPEHTVPTLEDDGNYIWDSHAIIAYLVSKYADSDALYPRDL 90
            |..:::..|:..||      |.|..|:|  |.....||.::...:  ||:.:         ||..
Frog   663 VKTDVNKIEEFLEERLTMPRYPKLAPKH--PESSSAGNDVFAKFS--AYIKN---------PRKD 714

  Fly    91 LQRAVVDQRLHFETGVVFANGIKAITKPLFFNGLNRIPKERYDAIVEIYDFVETFLAGHDYIAGD 155
            |..|:       |.|  |...::.:..  |.|  ..:|.|     ::.|...:..::...::.|:
Frog   715 LNAAL-------EKG--FLRSLRKLDD--FLN--TPLPDE-----IDAYSTEDITISDRKFLDGN 761

  Fly   156 QLTIADFSLISSITSLVAFVEIDRLKY 182
            :||:||.:|:..:    ..:::...||
Frog   762 ELTLADCNLLPKL----QIIKVVAKKY 784

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE5	NP_611327.1	GstA	4..196	CDD:223698	33/157 (21%)
		Thioredoxin_like	4..77	CDD:294274	13/50 (26%)
		GST_C_Delta_Epsilon	91..209	CDD:198287	18/92 (20%)
clic6	XP_002941923.2	PHA03418	<8..131	CDD:177646
		GST_N_CLIC	595..683	CDD:239359	4/19 (21%)
		O-ClC	598..831	CDD:129941	33/157 (21%)
		GST_C_CLIC6	690..829	CDD:198334	26/130 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910