DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment GstE4 and EEF1E1

DIOPT Version :9

Sequence 1:	NP_611326.1	Gene:	GstE4 / 37109	FlyBaseID:	FBgn0063496	Length:	222	Species:	Drosophila melanogaster
Sequence 2:	NP_004271.1	Gene:	EEF1E1 / 9521	HGNCID:	3212	Length:	174	Species:	Homo sapiens

Alignment Length:	170	Identity:	36/170 - (21%)
Similarity:	72/170 - (42%)	Gaps:	30/170 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 VNLFEKENFSEDFSKKNP-----QHTVPLLQDDDA-CIWDSHAIMAYLVEKYAPSDELYPKDLLQ 92
            ::|.||   |...||.|.     :..:|:||.::. .:.....|.|:|| |.|..:.|......:
Human     7 LSLLEK---SLGLSKGNKYSAQGERQIPVLQTNNGPSLTGLTTIAAHLV-KQANKEYLLGSTAEE 67

  Fly    93 RAKVDQLMHFESGVIFESALRRLTRPVLFFGEPTLPRNQVDHILQVYDFVETFLDDHDFVAGDQL 157
            :|.|.|.:.:           |:|:.     :....:|.:..:|:   .:.::|:|..::.|...
Human    68 KAIVQQWLEY-----------RVTQV-----DGHSSKNDIHTLLK---DLNSYLEDKVYLTGYNF 113

  Fly   158 TIADFSIVSTITSIGVFLEL-DPAKYPKIAAWLERLKELP 196
            |:||..:...:....|.|.: :..||..::.|...::..|
Human   114 TLADILLYYGLHRFIVDLTVQEKEKYLNVSRWFCHIQHYP 153

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE4	NP_611326.1	GST_N_Delta_Epsilon	4..77	CDD:239343	13/48 (27%)
		GstA	6..196	CDD:223698	35/168 (21%)
		GST_C_Delta_Epsilon	91..209	CDD:198287	19/107 (18%)
EEF1E1	NP_004271.1	N-terminal	2..56		15/52 (29%)
		Linker	57..63		1/5 (20%)
		C-terminal	64..152		18/106 (17%)
		GST_C_AIMP3	65..165	CDD:198338	19/108 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900