Protein Alignment GstE4 and CLIC3

DIOPT Version :10

• Sequence 1: NP_611326.1
• Gene: GstE4 / 37109
• FlyBaseID: FBgn0063496
• Length: 222
• Species: Drosophila melanogaster
• Sequence 2: NP_004660.2
• Gene: CLIC3 / 9022
• HGNCID: 2064
• Length: 236
• Species: Homo sapiens
• Alignment Length: 179
• Identity: 43/179 - (24%)
• Similarity: 67/179 - (37%)
• Gaps: 38/179 - (21%)

  Fly    13 PPTRACLLTLKALDLPFEFVFVNLFEKENFSEDFSKKNPQHTVPLLQDDDACIWDSHAIMAYLVE 77
            |..:...:.|....:||....|:.....:..:||:   |...:|:|..|.....|:..|..:|.|
Human    23 PSCQRLFMVLLLKGVPFTLTTVDTRRSPDVLKDFA---PGSQLPILLYDSDAKTDTLQIEDFLEE 84

  Fly    78 KYAPSD--ELYPKDLLQRAKVDQLMHFESGVI-----------FESALRRLTRPVLFFGEPTLPR 129
            ...|.|  .|.|:........:.:.|..|..|           ::..||.|.|...:...|
Human    85 TLGPPDFPSLAPRYRESNTAGNDVFHKFSAFIKNPVPAQDEALYQQLLRALARLDSYLRAP---- 145

  Fly   130 NQVDHIL----QVYDFVETFLDDHDFVAGDQLTIADFS------IVSTI 168
              ::|.|    |:.:....|||      ||:||:||.|      ||.|:
Human   146 --LEHELAGEPQLRESRRRFLD------GDRLTLADCSLLPKLHIVDTV 186

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GstE4	NP_611326.1	GstA	6..209	CDD:440390	43/179 (24%)
CLIC3	NP_004660.2	Required for insertion into the membrane. /evidence=ECO:0000250	1..88		15/67 (22%)
		O-ClC	5..229	CDD:129941	43/179 (24%)
		G-site. /evidence=ECO:0000305|PubMed:28198360, ECO:0000305|PubMed:37759794	22..25		1/1 (100%)