DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstE4 and CAM1

DIOPT Version :9

Sequence 1:	NP_611326.1	Gene:	GstE4 / 37109	FlyBaseID:	FBgn0063496	Length:	222	Species:	Drosophila melanogaster
Sequence 2:	NP_015277.1	Gene:	CAM1 / 856059	SGDID:	S000005969	Length:	415	Species:	Saccharomyces cerevisiae

Alignment Length:	191	Identity:	44/191 - (23%)
Similarity:	81/191 - (42%)	Gaps:	20/191 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 LKALDLPFEFVFVNLFEKENFSEDFS-KKNPQHTVPLLQDDDACIWDSHAIMAYLVEKYAPSDEL 85
            :|||.|..:.|..:. ..|.|:.||. ||.|....|    ....:.::.||..||| |.:..|::
Yeast    21 VKALKLDVKVVTPDA-AAEQFARDFPLKKVPAFVGP----KGYKLTEAMAINYYLV-KLSQDDKM 79

  Fly    86 YPKDLLQRAKVD-----QLMHFESGVIFESALRRLTRPVLFFGEPTLPRNQVDHIL----QVYDF 141
              |..|..|..|     |::.::|....:..::.....|...|.....:..||..:    ::.|.
Yeast    80 --KTQLLGADDDLNAQAQIIRWQSLANSDLCIQIANTIVPLKGGAPYNKKSVDSAMDAVDKIVDI 142

  Fly   142 VETFLDDHDFVAGDQLTIADFSIVSTITSI--GVFLELDPAKYPKIAAWLERLKELPYYEE 200
            .|..|.::.::|.:.:::||....|..|..  .:|.....|::|.|..|...::..|:.::
Yeast   143 FENRLKNYTYLATENISLADLVAASIFTRYFESLFGTEWRAQHPAIVRWFNTVRASPFLKD 203

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE4	NP_611326.1	GST_N_Delta_Epsilon	4..77	CDD:239343	17/55 (31%)
		GstA	6..196	CDD:223698	43/185 (23%)
		GST_C_Delta_Epsilon	91..209	CDD:198287	23/121 (19%)
CAM1	NP_015277.1	GST_N_EF1Bgamma	4..73	CDD:239342	18/57 (32%)
		GST_C_EF1Bgamma_like	92..214	CDD:198290	20/112 (18%)
		EF1G	255..359	CDD:395522
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157345091
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740