DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment GstE4 and TEF4

DIOPT Version :9

Sequence 1:	NP_611326.1	Gene:	GstE4 / 37109	FlyBaseID:	FBgn0063496	Length:	222	Species:	Drosophila melanogaster
Sequence 2:	NP_012842.1	Gene:	TEF4 / 853781	SGDID:	S000001564	Length:	412	Species:	Saccharomyces cerevisiae

Alignment Length:	214	Identity:	50/214 - (23%)
Similarity:	92/214 - (42%)	Gaps:	36/214 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGKISLYGLDASPPTRA--CLLTLKALDLPFEFVFVNLFEKENFSEDFSKKNPQHTVP-LLQDDD 62
            |.:.:|| ::.||...|  .|::...||       |.:.:.|..|| |:...|....| .|....
Yeast     1 MSQGTLY-INRSPRNYASEALISYFKLD-------VKIVDLEQSSE-FASLFPLKQAPAFLGPKG 56

  Fly    63 ACIWDSHAIMAYLVEKYAPSDE---LYPKDLLQRAKVDQLMHFESGVIFESALRRLTRPVLFFGE 124
            ..:.::.||..||..:.|...|   |...|:::::   |::.:.| :.....:..:.||.|.| :
Yeast    57 LKLTEALAIQFYLANQVADEKERARLLGSDVIEKS---QILRWAS-LANSDVMSNIARPFLSF-K 116

  Fly   125 PTLPRN---------QVDHILQVYDFVETFLDDHDFVAGDQLTIADFSIVSTITSIGVFLELDP- 179
            ..:|.|         ::|::..|:|   ..|.|:.|||.:.:::.|.....: .:.|:...|.|
Yeast   117 GLIPYNKKDVDACFVKIDNLAAVFD---ARLRDYTFVATENISLGDLHAAGS-WAFGLATILGPE 177

  Fly   180 --AKYPKIAAWLERLKELP 196
              ||:|.:..|...:...|
Yeast   178 WRAKHPHLMRWFNTVAASP 196

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE4	NP_611326.1	GST_N_Delta_Epsilon	4..77	CDD:239343	20/75 (27%)
		GstA	6..196	CDD:223698	48/207 (23%)
		GST_C_Delta_Epsilon	91..209	CDD:198287	25/118 (21%)
TEF4	NP_012842.1	GST_N_EF1Bgamma	4..72	CDD:239342	20/76 (26%)
		GST_C_EF1Bgamma_like	89..211	CDD:198290	25/117 (21%)
		EF1G	253..356	CDD:395522
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157345104
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830