DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment GstE4 and GstD10

DIOPT Version :9

Sequence 1:	NP_611326.1	Gene:	GstE4 / 37109	FlyBaseID:	FBgn0063496	Length:	222	Species:	Drosophila melanogaster
Sequence 2:	NP_001287302.1	Gene:	GstD10 / 59240	FlyBaseID:	FBgn0042206	Length:	210	Species:	Drosophila melanogaster

Alignment Length:	208	Identity:	72/208 - (34%)
Similarity:	118/208 - (56%)	Gaps:	6/208 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 ISLYGLDASPPTRACLLTLKALDLPFE-FVFVNLFEKENFSEDFSKKNPQHTVPLLQDDDACIWD 67
            :.||....|.|.|:.|:|.|||.:.|: ...:|...:|.|:.::.|.|||||:|.|.|....:|:
  Fly     1 MDLYYRPGSAPCRSVLMTAKALGVEFDKKTIINTRAREQFTPEYLKINPQHTIPTLHDHGFALWE 65

  Fly    68 SHAIMAYLVEKYAPSDELYPKDLLQRAKVDQLMHFESGVIFESALRRLTRPVLFFGEPTLPRNQV 132
            |.|||.||||||...|:|:|||:.::|.::|.::|:.|.:::| ......|.:|..:|....| .
  Fly    66 SRAIMVYLVEKYGKDDKLFPKDVQKQALINQRLYFDMGTLYKS-FSEYYYPQIFLKKPANEEN-Y 128

  Fly   133 DHILQVYDFVETFLDDHDFVAGDQLTIADFSIVSTITSIGVFLELDPAKYPKIAAWLERLKEL-P 196
            ..|...::|:.|||:...:.||...::||.:.::|:::..| ...|..:|..:|.|.|..|:| |
  Fly   129 KKIEVAFEFLNTFLEGQTYSAGGDYSLADIAFLATVSTFDV-AGFDFKRYANVARWYENAKKLTP 192

  Fly   197 YYEEANGKGAAQF 209
            .:|| |..|..:|
  Fly   193 GWEE-NWAGCQEF 204

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE4	NP_611326.1	GST_N_Delta_Epsilon	4..77	CDD:239343	30/73 (41%)
		GstA	6..196	CDD:223698	66/191 (35%)
		GST_C_Delta_Epsilon	91..209	CDD:198287	32/118 (27%)
GstD10	NP_001287302.1	GST_N_Delta_Epsilon	1..75	CDD:239343	30/73 (41%)
		PLN02473	3..196	CDD:166114	67/195 (34%)
		GST_C_Delta_Epsilon	89..205	CDD:198287	33/120 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45460277
Domainoid	1	1.000	54	1.000	Domainoid score	I4138
eggNOG	1	0.900	-	-		E1_COG0625
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	77	1.000	Inparanoid score	I2398
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1231780at2759
OrthoFinder	1	1.000	-	-		FOG0000035
OrthoInspector	1	1.000	-	-		mtm975
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR43969
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X30
	10	9.900