DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstE4 and GstD8

DIOPT Version :9

Sequence 1:	NP_611326.1	Gene:	GstE4 / 37109	FlyBaseID:	FBgn0063496	Length:	222	Species:	Drosophila melanogaster
Sequence 2:	NP_524916.1	Gene:	GstD8 / 48341	FlyBaseID:	FBgn0010044	Length:	212	Species:	Drosophila melanogaster

Alignment Length:	217	Identity:	77/217 - (35%)
Similarity:	125/217 - (57%)	Gaps:	9/217 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 ISLYGLDASPPTRACLLTLKALDLPFEFVFVNLFEKENFSEDFSKKNPQHTVPLLQDDDACIWDS 68
            :..|....|.|.|:.::|.|||.:......:.:.:.|....:|.|.||||.:|.|.||...||:|
  Fly     1 MDFYYHPCSAPCRSVIMTAKALGVDLNMKLLKVMDGEQLKPEFVKLNPQHCIPTLVDDGFSIWES 65

  Fly    69 HAIMAYLVEKYAPSDELYPKDLLQRAKVDQLMHFESGVIFESALRRLTRPVLFFGEPTLPR--NQ 131
            .||:.||||||...|.|||.|..::|.|:|.::|:.|.:|:|.:..: .|.:....|..|.  .:
  Fly    66 RAILIYLVEKYGADDSLYPSDPQKKAVVNQRLYFDMGTLFQSFVEAI-YPQIRNNHPADPEAMQK 129

  Fly   132 VDHILQVYDFVETFLDDHDFVAGDQLTIADFSIVSTITSIGVFLELDPAKYPKIAAWLERLKEL- 195
            ||   ..:..::|||:|.::||||.|||||.::::::::..| ::.|.|:||.:|.|.|..||:
  Fly   130 VD---SAFGHLDTFLEDQEYVAGDCLTIADIALLASVSTFEV-VDFDIAQYPNVARWYENAKEVT 190

  Fly   196 PYYEEANGKGAAQFVELLRSKN 217
            |.:|| |..|.....:|::.:|
  Fly   191 PGWEE-NWDGVQLIKKLVQERN 211

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE4	NP_611326.1	GST_N_Delta_Epsilon	4..77	CDD:239343	26/72 (36%)
		GstA	6..196	CDD:223698	70/192 (36%)
		GST_C_Delta_Epsilon	91..209	CDD:198287	40/120 (33%)
GstD8	NP_524916.1	GstA	1..188	CDD:223698	68/191 (36%)
		GST_N_Delta_Epsilon	1..74	CDD:239343	26/72 (36%)
		GST_C_Delta_Epsilon	88..204	CDD:198287	40/121 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45460264
Domainoid	1	1.000	54	1.000	Domainoid score	I4138
eggNOG	1	0.900	-	-		E1_COG0625
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	77	1.000	Inparanoid score	I2398
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D118089at33392
OrthoFinder	1	1.000	-	-		FOG0000035
OrthoInspector	1	1.000	-	-		mtm975
orthoMCL	1	0.900	-	-		OOG6_100130
Panther	1	1.100	-	-	P	PTHR43969
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X30
	11	10.800