DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstE4 and GstD2

DIOPT Version :9

Sequence 1:	NP_611326.1	Gene:	GstE4 / 37109	FlyBaseID:	FBgn0063496	Length:	222	Species:	Drosophila melanogaster
Sequence 2:	NP_524912.1	Gene:	GstD2 / 48335	FlyBaseID:	FBgn0010038	Length:	215	Species:	Drosophila melanogaster

Alignment Length:	203	Identity:	72/203 - (35%)
Similarity:	115/203 - (56%)	Gaps:	5/203 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 ISLYGLDASPPTRACLLTLKALDLPFEFVFVNLFEKENFSEDFSKKNPQHTVPLLQDDDACIWDS 68
            :..|.:......|..::..|||.|......:|..|.|....:|.|.|||||:|.|.|:...||:|
  Fly     1 MDFYYMPGGGGCRTVIMVAKALGLELNKKLLNTMEGEQLKPEFVKLNPQHTIPTLVDNGFSIWES 65

  Fly    69 HAIMAYLVEKYAPSDELYPKDLLQRAKVDQLMHFESGVIFESALRRLTRPVLFFGEPTLPRNQVD 133
            .||..||||||...|.|.|.|..:||.::|.::|:.|.::|| ..:...|:...|:|....: :.
  Fly    66 RAIAVYLVEKYGKDDYLLPNDPKKRAVINQRLYFDMGTLYES-FAKYYYPLFRTGKPGSDED-LK 128

  Fly   134 HILQVYDFVETFLDDHDFVAGDQLTIADFSIVSTITSIGVFLELDPAKYPKIAAWLERLKEL-PY 197
            .|...:.|::|||:..::|||||||:||.:|:||:::..| .|.|.:||..::.|.:..|:: |.
  Fly   129 RIETAFGFLDTFLEGQEYVAGDQLTVADIAILSTVSTFEV-SEFDFSKYSNVSRWYDNAKKVTPG 192

  Fly   198 YEEANGKG 205
            ::| |.:|
  Fly   193 WDE-NWEG 199

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE4	NP_611326.1	GST_N_Delta_Epsilon	4..77	CDD:239343	26/72 (36%)
		GstA	6..196	CDD:223698	68/190 (36%)
		GST_C_Delta_Epsilon	91..209	CDD:198287	38/116 (33%)
GstD2	NP_524912.1	GST_N_Delta_Epsilon	1..74	CDD:239343	26/72 (36%)
GstD2	NP_524912.1	GST_C_Delta_Epsilon	88..204	CDD:198287	38/116 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45460251
Domainoid	1	1.000	54	1.000	Domainoid score	I4138
eggNOG	1	0.900	-	-		E1_COG0625
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	77	1.000	Inparanoid score	I2398
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1231780at2759
OrthoFinder	1	1.000	-	-		FOG0000035
OrthoInspector	1	1.000	-	-		mtm975
orthoMCL	1	0.900	-	-		OOG6_100130
Panther	1	1.100	-	-	P	PTHR43969
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X30
	11	10.800