DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstE4 and GstD11

DIOPT Version :9

Sequence 1:	NP_611326.1	Gene:	GstE4 / 37109	FlyBaseID:	FBgn0063496	Length:	222	Species:	Drosophila melanogaster
Sequence 2:	NP_001138040.1	Gene:	GstD11 / 41512	FlyBaseID:	FBgn0038029	Length:	243	Species:	Drosophila melanogaster

Alignment Length:	225	Identity:	86/225 - (38%)
Similarity:	122/225 - (54%)	Gaps:	17/225 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 GKIS---LYGLDASPPTRACLLTLKALDLPFEFVFVNLFEKENFSEDFSKKNPQHTVPLLQDDDA 63
            ||:|   ||.|..|||.|:.||..|.||:.||...||:.|.|....||...||||.||.:.|:..
  Fly    20 GKMSPPVLYYLPPSPPCRSILLLAKMLDIDFELKIVNILEGEQLKPDFVAMNPQHCVPTMNDEGL 84

  Fly    64 CIWDSHAIMAYLVEKYAPSDELYPKDLLQRAKVDQLMHFESGVIFESALRRLTR---PVLFFGEP 125
            .:|:|.||::|||..|..||:|||.|:..||.|||.:.|:.|.::    .|||.   |.:|.|.|
  Fly    85 VLWESRAILSYLVAAYGKSDQLYPTDIRVRALVDQRLQFDLGTLY----MRLTDYYFPTMFIGAP 145

  Fly   126 TLPRNQVDHILQVYDFVETFLDDHDFVAGDQLTIADFSIVSTITSIGVF-LELDPAKYPKIAAWL 189
             |...:...:.:...::.|.|:...|.|.|..||||.:::.|::.:..| .||.|  |..|..||
  Fly   146 -LDEGKRAKLAEAVGWLNTILEGRQFSAADHFTIADLTLLVTVSQLEAFEFELRP--YKHIRQWL 207

  Fly   190 ERLKE--LPY-YEEANGKGAAQFVELLRSK 216
            :|.|:  .|: |||.|...|....::.::|
  Fly   208 DRCKDHMAPFDYEELNANKANMLADMFKAK 237

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE4	NP_611326.1	GST_N_Delta_Epsilon	4..77	CDD:239343	34/75 (45%)
		GstA	6..196	CDD:223698	76/195 (39%)
		GST_C_Delta_Epsilon	91..209	CDD:198287	41/124 (33%)
GstD11	NP_001138040.1	GST_N_Delta_Epsilon	25..98	CDD:239343	33/72 (46%)
GstD11	NP_001138040.1	GST_C_Delta_Epsilon	112..231	CDD:198287	41/125 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	54	1.000	Domainoid score	I4138
eggNOG	1	0.900	-	-		E1_COG0625
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	77	1.000	Inparanoid score	I2398
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1231780at2759
OrthoFinder	1	1.000	-	-		FOG0000035
OrthoInspector	1	1.000	-	-		mtm975
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR43969
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X30
	9	8.970