DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstE4 and GstE2

DIOPT Version :9

Sequence 1:	NP_611326.1	Gene:	GstE4 / 37109	FlyBaseID:	FBgn0063496	Length:	222	Species:	Drosophila melanogaster
Sequence 2:	NP_611324.1	Gene:	GstE2 / 37107	FlyBaseID:	FBgn0063498	Length:	221	Species:	Drosophila melanogaster

Alignment Length:	212	Identity:	106/212 - (50%)
Similarity:	151/212 - (71%)	Gaps:	1/212 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 KISLYGLDASPPTRACLLTLKALDLPFEFVFVNLFEKENFSEDFSKKNPQHTVPLLQDDDACIWD 67
            |:.|||:|.|||.|||.|||:||:|.:|:..::|...::|.:.|.|||||||||||:|:.|.|||
  Fly     4 KLVLYGMDISPPVRACKLTLRALNLDYEYKEMDLLAGDHFKDAFLKKNPQHTVPLLEDNGALIWD 68

  Fly    68 SHAIMAYLVEKYAPSDELYPKDLLQRAKVDQLMHFESGVIFESALRRLTRPVLFFGEPTLPRNQV 132
            ||||:.|||:|||.||||||:||:.||:|||.:.|::.::|.| ||.::.|........:|:.:|
  Fly    69 SHAIVCYLVDKYANSDELYPRDLVLRAQVDQRLFFDASILFMS-LRNVSIPYFLRQVSLVPKEKV 132

  Fly   133 DHILQVYDFVETFLDDHDFVAGDQLTIADFSIVSTITSIGVFLELDPAKYPKIAAWLERLKELPY 197
            |:|...|..:|.||.|:.::.|.||||||....:|.:|:...|:||..||||:|||.|||.:||:
  Fly   133 DNIKDAYGHLENFLGDNPYLTGSQLTIADLCCGATASSLAAVLDLDELKYPKVAAWFERLSKLPH 197

  Fly   198 YEEANGKGAAQFVELLR 214
            |||.|.:|..:::.||:
  Fly   198 YEEDNLRGLKKYINLLK 214

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE4	NP_611326.1	GST_N_Delta_Epsilon	4..77	CDD:239343	42/72 (58%)
		GstA	6..196	CDD:223698	96/189 (51%)
		GST_C_Delta_Epsilon	91..209	CDD:198287	49/117 (42%)
GstE2	NP_611324.1	GstA	5..196	CDD:223698	96/191 (50%)
		GST_N_Delta_Epsilon	5..78	CDD:239343	42/72 (58%)
		GST_C_Delta_Epsilon	94..209	CDD:198287	49/115 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45467968
Domainoid	1	1.000	54	1.000	Domainoid score	I4138
eggNOG	1	0.900	-	-		E1_COG0625
Homologene	1	1.000	-	-		H120001
Inparanoid	1	1.050	77	1.000	Inparanoid score	I2398
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D118089at33392
OrthoFinder	1	1.000	-	-		FOG0000035
OrthoInspector	1	1.000	-	-		mtm975
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR43969
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X30
	11	10.900