DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment GstE4 and GstT3

DIOPT Version :9

Sequence 1:	NP_611326.1	Gene:	GstE4 / 37109	FlyBaseID:	FBgn0063496	Length:	222	Species:	Drosophila melanogaster
Sequence 2:	NP_001162808.1	Gene:	GstT3 / 33047	FlyBaseID:	FBgn0031117	Length:	268	Species:	Drosophila melanogaster

Alignment Length:	210	Identity:	65/210 - (30%)
Similarity:	105/210 - (50%)	Gaps:	28/210 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 SPPTRACLLTLKALDLPFEFVFVNLFEKENFSEDFSKK-NPQHTVPLLQDDDACIWDSHAIMAYL 75
            |.|:||..:..:..::|||...|.|...|:.:|||.|: |....||.:.|:...:.:|.||:.||
  Fly    53 SQPSRALFIIFRLSNMPFEDCVVALRNGEHLTEDFKKEINRFQRVPCIHDNGYKLAESVAILRYL 117

  Fly    76 VEKYAPSDELYPKDLLQRAKVDQLMHFESGVIFESALRRLTRPVLF---FGEPTLP--------- 128
            ..|....:.||||..:.:::||:.:.::...:      |||..:.|   :.||.|.
  Fly   118 SAKGKIPEHLYPKYFVDQSRVDEFLEWQHMSL------RLTCAMYFRTVWLEPLLTGRTPSEAKI 176

  Fly   129 ---RNQVDHILQVYDFVETFLDDHDFVAGDQLTIADFSIVSTITSIGVFLELD-PAKYPKIAAWL 189
               |.|::..|.|.:  |.:|:..||:.|..||:||......|....: .:.| ..|||||.|||
  Fly   177 ETFRMQMERNLDVVE--EVWLEGKDFLTGSSLTVADIFAACEIEQTRM-ADYDVRIKYPKIRAWL 238

  Fly   190 ERLKEL--PYYEEAN 202
            :|:::.  |||:.|:
  Fly   239 KRVRQSCNPYYDVAH 253

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE4	NP_611326.1	GST_N_Delta_Epsilon	4..77	CDD:239343	23/65 (35%)
		GstA	6..196	CDD:223698	61/202 (30%)
		GST_C_Delta_Epsilon	91..209	CDD:198287	37/130 (28%)
GstT3	NP_001162808.1	GST_N_Theta	45..121	CDD:239348	23/67 (34%)
		GstA	47..243	CDD:223698	61/198 (31%)
		GST_C_Theta	135..259	CDD:198292	37/128 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45460073
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1231780at2759
OrthoFinder	1	1.000	-	-		FOG0000035
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100130
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X30
	7	6.650