back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment GstE4 and GSTT1

DIOPT Version :9

Sequence 1:	NP_611326.1	Gene:	GstE4 / 37109	FlyBaseID:	FBgn0063496	Length:	222	Species:	Drosophila melanogaster
Sequence 2:	NP_000844.2	Gene:	GSTT1 / 2952	HGNCID:	4641	Length:	240	Species:	Homo sapiens

Alignment Length:	231	Identity:	75/231 - (32%)
Similarity:	122/231 - (52%)	Gaps:	24/231 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGKISLYGLD-ASPPTRACLLTLKALDLPFEFVFVNLFEKENFSEDFSKKNPQHTVPLLQDDDAC 64
            || :.|| || .|.|.||..:..|..|:|||...|:|.:.::.|:.|::.||...||.|:|.|..
Human     1 MG-LELY-LDLLSQPCRAVYIFAKKNDIPFELRIVDLIKGQHLSDAFAQVNPLKKVPALKDGDFT 63

  Fly    65 IWDSHAIMAYLVEKYAPSDELYPKDLLQRAKVDQLMHFESGVIFESALRRLTRPVL---FFGEPT 126
            :.:|.||:.||..||...|..||:||..||:||:.:.::...:..|.||.|...|:   |.|||.
Human    64 LTESVAILLYLTRKYKVPDYWYPQDLQARARVDEYLAWQHTTLRRSCLRALWHKVMFPVFLGEPV 128

  Fly   127 LPRN------QVDHILQVYDFVETFLDDHDFVAGDQLTIADF-SIVSTITSIGVFLELDPAKYPK 184
            .|:.      ::|..||:.:  :.||.:..|:.|..:::||. :|...:..:|...::...: ||
Human   129 SPQTLAATLAELDVTLQLLE--DKFLQNKAFLTGPHISLADLVAITELMHPVGAGCQVFEGR-PK 190

  Fly   185 IAAWLERLKELPYYEEANGKGAAQFVE--LLRSKNF 218
            :|.|.:|:      |.|.|:...|...  :|::|:|
Human   191 LATWRQRV------EAAVGEDLFQEAHEVILKAKDF 220

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.