Protein Alignment GstE4 and GSTT4

DIOPT Version :10

• Sequence 1: NP_611326.1
• Gene: GstE4 / 37109
• FlyBaseID: FBgn0063496
• Length: 222
• Species: Drosophila melanogaster
• Sequence 2: NP_001345593.1
• Gene: GSTT4 / 25774
• HGNCID: 26930
• Length: 241
• Species: Homo sapiens
• Alignment Length: 200
• Identity: 55/200 - (27%)
• Similarity: 92/200 - (46%)
• Gaps: 23/200 - (11%)

  Fly     4 ISLYGLDASPPTRACLLTLKALDLPFEFVFVNLFEKENFSEDFSKKNPQHTVPLLQDDDACIWDS 68
            :.||....|.|.||..:..|..|:.|.|.||:|.:..:.|:.:...||...:|.|:|....:.:|
Human     3 LELYMDLLSAPCRAVYIFSKKHDIQFNFQFVDLLKGHHHSKGYIDINPLRKLPSLKDGKFILSES 67

  Fly    69 HAIMAYLVEKYAPSDELYPKDLLQRAKVDQLMHFESGVIFESALRRLTRPVLFF----GEPTLPR 129
            .||:.||..||:......|.|...||:||:.:.::. ..|:..::::....|..    ||.....
Human    68 AAILYYLCRKYSAPSHWCPPDPHARARVDEFVAWQH-TAFQLPMKKIVWLKLLIPKITGEEVSAE 131

  Fly   130 ------NQVDHILQVYDFVETFLDDHDFVAGDQLTIADFSIVSTI-----TSIGVFLELDPAKYP 183
                  .:|.:.||:::  |.||.|..|:.|:|:::||...|..:     .:..|||...
Human   132 KMEHAVEEVKNSLQLFE--EYFLQDKMFITGNQISLADLVAVVEMMQPMAANYNVFLNSS----- 189

  Fly   184 KIAAW 188
            |:|.|
Human   190 KLAEW 194

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GstE4	NP_611326.1	GstA	6..209	CDD:440390	54/197 (27%)
GSTT4	NP_001345593.1	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold	3..78	CDD:469754	24/74 (32%)
		GST_C_Theta	91..217	CDD:198292	26/111 (23%)