DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstE4 and gst2

DIOPT Version :9

Sequence 1:	NP_611326.1	Gene:	GstE4 / 37109	FlyBaseID:	FBgn0063496	Length:	222	Species:	Drosophila melanogaster
Sequence 2:	NP_588517.1	Gene:	gst2 / 2539601	PomBaseID:	SPCC965.07c	Length:	230	Species:	Schizosaccharomyces pombe

Alignment Length:	243	Identity:	69/243 - (28%)
Similarity:	107/243 - (44%)	Gaps:	43/243 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGKISLYGLDASPPTRACLLTLKALDLPFEFVFVNLFEKENFSEDFSKKNPQHTVPLLQD---DD 62
            |...:||.....|.....:|.||.|:|.:|.:|.:..:.|...::....||...||.|.|   :|
pombe     1 MAHFTLYSHAGGPNPWKVVLALKELNLSYEQIFYDFQKGEQKCKEHLALNPNGRVPTLVDHKNND 65

  Fly    63 ACIWDSHAIMAYLVEKYAPSDEL-YPKDLLQRAKVDQLMHFES---GVIFESA--LRRLTRPVLF 121
            ..||:|.||:.||.:||....:: ...|..:..|:.|.:.|::   |||:..|  ..      .|
pombe    66 YTIWESDAILIYLADKYDTDRKISLSFDDPEYYKLIQYLFFQASGQGVIWGQAGWFN------FF 124

  Fly   122 FGEP-----TLPRNQVDHILQVYDFVETFLDDHDFVAGDQLTIADFSIVSTITSIGVFL------ 175
            ..||     |..||::..:|.|   :|..|.|.|::..::.||||.|.:....::|...
pombe   125 HHEPVVSAVTRYRNEIKRVLGV---LEDILKDRDYLVANKYTIADLSFIPWNYNLGGLFGEGKFS 186

  Fly   176 ------ELDPAK-YPKIAAWLERLKELPYYEEANGKGAAQFVELLRSK 216
                  :||..| :||..||.:||...|..:       |.|.||.::|
pombe   187 FKEEVPQLDFEKEFPKAYAWNQRLLARPAVK-------ATFEELAKAK 227

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE4	NP_611326.1	GST_N_Delta_Epsilon	4..77	CDD:239343	25/75 (33%)
		GstA	6..196	CDD:223698	62/216 (29%)
		GST_C_Delta_Epsilon	91..209	CDD:198287	36/140 (26%)
gst2	NP_588517.1	GST_N_Ure2p_like	4..84	CDD:239346	27/79 (34%)
		GstA	5..226	CDD:223698	67/236 (28%)
		GST_C_Ure2p	96..219	CDD:198326	35/138 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	80	1.000	Inparanoid score	I1854
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000035
OrthoInspector	1	1.000	-	-		mtm9258
orthoMCL	1	0.900	-	-		OOG6_100130
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X30
TreeFam	0	0.000	Not matched by this tool.
	8	7.760