DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstE4 and gst1

DIOPT Version :9

Sequence 1:	NP_611326.1	Gene:	GstE4 / 37109	FlyBaseID:	FBgn0063496	Length:	222	Species:	Drosophila melanogaster
Sequence 2:	NP_588298.1	Gene:	gst1 / 2538694	PomBaseID:	SPCC191.09c	Length:	229	Species:	Schizosaccharomyces pombe

Alignment Length:	247	Identity:	71/247 - (28%)
Similarity:	109/247 - (44%)	Gaps:	53/247 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGKISLYGLDASPPTRACLLTLKALDLPFEFVFVNLFEKENFSEDFSKKNPQHTVPLLQD---DD 62
            |.:.:|:.....|.....:..||.|||.:|..:||..:.|..|.:....||...||.|.|   :|
pombe     1 MAQFTLWSHAHGPNPWKVVQALKELDLTYETRYVNFSKNEQKSPEHLALNPNGRVPTLIDHHNND 65

  Fly    63 ACIWDSHAIMAYLVEKYAPSDEL-YPKDLLQRAKVDQLMHFES---GVIF-----------ESAL 112
            ..||:|.||:.||.:||....:: .|:|..:..||.|.:.|::   |:|:           |..:
pombe    66 YTIWESDAILIYLADKYDTERKISLPRDHPEYYKVIQYLFFQASGQGIIWGQAGWFSVYHQELVI 130

  Fly   113 RRLTRPVLFFGEPTLPRNQVDHILQVYDFVETFLDDHDFVAGDQLTIADFSIVS------TITSI 171
            ..:||          .||::..:|.|   :|..|.|.|::..::.||||.|.:|      .|.:.
pombe   131 SAITR----------YRNEIKRVLGV---LEDILKDRDYLVANRFTIADLSFISWNNFLEIIFAE 182

  Fly   172 GVFL------ELDPAK-YPKIAAWLERLKELPYYEEANGKGAAQFVELLRSK 216
            |.|.      :||..| :|:..:|.:||...|       ...|.|.|  |||
pombe   183 GKFSIEEEVPQLDFEKEFPRTYSWHQRLLARP-------ASKATFEE--RSK 225

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE4	NP_611326.1	GST_N_Delta_Epsilon	4..77	CDD:239343	26/75 (35%)
		GstA	6..196	CDD:223698	63/220 (29%)
		GST_C_Delta_Epsilon	91..209	CDD:198287	35/144 (24%)
gst1	NP_588298.1	GST_N_Ure2p_like	3..84	CDD:239346	28/80 (35%)
		GstA	5..218	CDD:223698	64/232 (28%)
		GST_C_Ure2p	96..219	CDD:198326	34/142 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	80	1.000	Inparanoid score	I1854
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000035
OrthoInspector	1	1.000	-	-		mtm9258
orthoMCL	1	0.900	-	-		OOG6_100130
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X30
TreeFam	0	0.000	Not matched by this tool.
	8	7.760