DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstE4 and gst-42

DIOPT Version :9

Sequence 1:	NP_611326.1	Gene:	GstE4 / 37109	FlyBaseID:	FBgn0063496	Length:	222	Species:	Drosophila melanogaster
Sequence 2:	NP_509962.1	Gene:	gst-42 / 183911	WormBaseID:	WBGene00001790	Length:	214	Species:	Caenorhabditis elegans

Alignment Length:	189	Identity:	57/189 - (30%)
Similarity:	87/189 - (46%)	Gaps:	15/189 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 LTLKALDLPFEFVFVNLFEKENFSEDFSKKNPQHTVPLLQDDDACIWDSHAIMAYLVEKYAPSDE 84
            |.||.:|  :|:..|:|..:|..|: ..:.||...||....|...|.:|.||:.||.|.: |...
Worm    24 LALKNVD--YEYKTVDLLSEEAKSK-LKEINPAAKVPTFVVDGQVITESLAIIEYLEETH-PDVP 84

  Fly    85 LYPKDLLQRAKVDQL-MHFESGV--IFE-SALRRLTRPVLFFGEPTLPRNQVDHILQVYDFVETF 145
            |.|||.::||....: :...||:  :.. ..|:.|.:....||.....:..|:.:..    :|..
Worm    85 LLPKDPIKRAHARAISLLVASGIQPLHNLKVLQLLNKKEAGFGGQFAKQFVVEGLTA----LEIL 145

  Fly   146 LDDHD--FVAGDQLTIADFSIVSTITSIGVFLELDPAKYPKIAAWLERLKELPYYEEAN 202
            |..|.  :..||.:||||.||...|.|...| .||.:.||.:....|.|.::|.:..|:
Worm   146 LKQHSGKYAVGDDVTIADLSIPPLIYSANRF-NLDLSPYPTVNRINETLADIPAFIAAH 203

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE4	NP_611326.1	GST_N_Delta_Epsilon	4..77	CDD:239343	20/56 (36%)
		GstA	6..196	CDD:223698	55/181 (30%)
		GST_C_Delta_Epsilon	91..209	CDD:198287	31/118 (26%)
gst-42	NP_509962.1	GST_N_Zeta	6..77	CDD:239340	19/55 (35%)
		maiA	7..211	CDD:273527	57/189 (30%)
		GST_C_Zeta	90..207	CDD:198300	31/119 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810