Protein Alignment GstE4 and GSTO2

DIOPT Version :10

• Sequence 1: NP_611326.1
• Gene: GstE4 / 37109
• FlyBaseID: FBgn0063496
• Length: 222
• Species: Drosophila melanogaster
• Sequence 2: NP_899062.1
• Gene: GSTO2 / 119391
• HGNCID: 23064
• Length: 243
• Species: Homo sapiens
• Alignment Length: 209
• Identity: 48/209 - (22%)
• Similarity: 83/209 - (39%)
• Gaps: 39/209 - (18%)

  Fly     2 GKISLYGLDASPPTRACLLTLKALDLPFEFVFVNLFEKENFSEDFSKKNPQHTVPLLQDDDA-CI 65
            |.|.:|.:...|.:....|.|||.|:..|.|.:||   .|..|.:..|:|...:|:|:.... .|
Human    22 GLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINL---RNKPEWYYTKHPFGHIPVLETSQCQLI 83

  Fly    66 WDSHAIMAYLVEKYAPSDELYPKDLLQRAKVDQLMHFESGVIFESALRRLTRPVLFFGEPTLPR- 129
            ::|.....||.:.| |..:|:|.|..:||:...|:.                  ||...|.|.:
Human    84 YESVIACEYLDDAY-PGRKLFPYDPYERARQKMLLE------------------LFCKVPHLTKE 129

  Fly   130 ------------NQVDHILQVYDFVETFLD--DHDFVAGDQLTIADFSIVSTITSIGVFLELDPA 180
                        |....:.|.:..:|..|:  :..|..|..:::.|:.:......:.|:..||..
Human   130 CLVALRCGRECTNLKAALRQEFSNLEEILEYQNTTFFGGTCISMIDYLLWPWFERLDVYGILDCV 194

  Fly   181 KY-PKIAAWLERLK 193
            .: |.:..|:..:|
Human   195 SHTPALRLWISAMK 208

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GstE4	NP_611326.1	GstA	6..209	CDD:440390	46/205 (22%)
GSTO2	NP_899062.1	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold	7..94	CDD:469754	22/74 (30%)
		GST_C_Omega	108..230	CDD:198293	20/119 (17%)