DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstE4 and clic6

DIOPT Version :9

Sequence 1:	NP_611326.1	Gene:	GstE4 / 37109	FlyBaseID:	FBgn0063496	Length:	222	Species:	Drosophila melanogaster
Sequence 2:	XP_002941923.2	Gene:	clic6 / 100486547	XenbaseID:	XB-GENE-6039572	Length:	831	Species:	Xenopus tropicalis

Alignment Length:	219	Identity:	49/219 - (22%)
Similarity:	82/219 - (37%)	Gaps:	52/219 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 ISLY---GLDAS-----PPTRACLLTLKALDLPFEFVFVNLFEKENFSEDFSKKNPQHTVPLLQD 60
            |||:   |.|..     |.::...:.|....:.|....|:|..|   ..|.....|....|.:..
Frog   598 ISLFVKAGSDGESIGNCPFSQRLFMILWLKGVVFNVTTVDLKRK---PADLQNLAPGTNPPFMTF 659

  Fly    61 DDACIWDSHAIMAYLVE--------KYAP--------SDELYPK--DLLQRAKVDQLMHFESGVI 107
            |.....|.:.|..:|.|        |.||        .::::.|  ..::..:.|.....|.|
Frog   660 DGEVKTDVNKIEEFLEERLTMPRYPKLAPKHPESSSAGNDVFAKFSAYIKNPRKDLNAALEKG-- 722

  Fly   108 FESALRRLTRPVLFFGEPTLPRNQVDHILQVYDFVETFLDDHDFVAGDQLTIADFSIVSTITSIG 172
            |..:||:|..   |...| || :::|    .|...:..:.|..|:.|::||:||.:::..:..|
Frog   723 FLRSLRKLDD---FLNTP-LP-DEID----AYSTEDITISDRKFLDGNELTLADCNLLPKLQII- 777

  Fly   173 VFLELDPAKYPKIAAWLERLKELP 196
                       |:.|...|..|:|
Frog   778 -----------KVVAKKYRNFEIP 790

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE4	NP_611326.1	GST_N_Delta_Epsilon	4..77	CDD:239343	18/80 (23%)
		GstA	6..196	CDD:223698	46/215 (21%)
		GST_C_Delta_Epsilon	91..209	CDD:198287	26/106 (25%)
clic6	XP_002941923.2	PHA03418	<8..131	CDD:177646
		GST_N_CLIC	595..683	CDD:239359	19/87 (22%)
		O-ClC	598..831	CDD:129941	49/219 (22%)
		GST_C_CLIC6	690..829	CDD:198334	27/124 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910