Protein Alignment GstE3 and CLIC5

DIOPT Version :10

• Sequence 1: NP_611325.2
• Gene: GstE3 / 37108
• FlyBaseID: FBgn0063497
• Length: 220
• Species: Drosophila melanogaster
• Sequence 2: NP_001107558.1
• Gene: CLIC5 / 53405
• HGNCID: 13517
• Length: 410
• Species: Homo sapiens
• Alignment Length: 212
• Identity: 47/212 - (22%)
• Similarity: 78/212 - (36%)
• Gaps: 61/212 - (28%)

  Fly     8 GIDGS-----PPVRSVLLTLRALNLDFDYKIVNLMEKEHLKPEFLKINPLHTVPALDDNGFYLAD 67
            ||||.     |..:.:.:.|....:.|:...|:|..|   ..:...:.|....|.|..||....|
Human   182 GIDGESIGNCPFSQRLFMILWLKGVVFNVTTVDLKRK---PADLHNLAPGTHPPFLTFNGDVKTD 243

  Fly    68 SHAINSYLVSKYGRNDSLYPKDLKKRAIVDQRLHYDSSVVTSTGRAI--TFPLFWENKTEIPQAR 130
            .:.|..:|      .::|.|:...|.|    ..|.:|:   :.|..|  .|..:.:|..:...|.
Human   244 VNKIEEFL------EETLTPEKYPKLA----AKHRESN---TAGIDIFSKFSAYIKNTKQQNNAA 295

  Fly   131 ID-ALEGVYKSLNLFL---------------ENGN---YLAGDNLTIAD------FHVI------ 164
            :: .|....|.|:.:|               :.|:   :|.||.||:||      .||:
Human   296 LERGLTKALKKLDDYLNTPLPEEIDANTCGEDKGSRRKFLDGDELTLADCNLLPKLHVVKIVAKK 360

  Fly   165 -------AGLTGFFVFL 174
                   |.:||.:.:|
Human   361 YRNYDIPAEMTGLWRYL 377

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GstE3	NP_611325.2	GstA	4..200	CDD:440390	47/212 (22%)
CLIC5	NP_001107558.1	O-ClC	173..408	CDD:129941	47/212 (22%)
		G-site. /evidence=ECO:0000250|UniProtKB:O00299	191..194		1/2 (50%)