DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstE3 and GstD7

DIOPT Version :9

Sequence 1:	NP_611325.2	Gene:	GstE3 / 37108	FlyBaseID:	FBgn0063497	Length:	220	Species:	Drosophila melanogaster
Sequence 2:	NP_525114.1	Gene:	GstD7 / 48340	FlyBaseID:	FBgn0010043	Length:	224	Species:	Drosophila melanogaster

Alignment Length:	225	Identity:	82/225 - (36%)
Similarity:	128/225 - (56%)	Gaps:	13/225 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGKLTLYGIDGSPPVRSVLLTLRALNLDFDYKIVNLMEKEHLKPEFLKINPLHTVPALDDNGFYL 65
            |..|.||....:|..|::.:..:||.|:.:.|::|.||.:.|||||::|||.||:|.|.||||.:
  Fly     1 MPNLDLYNFPMAPASRAIQMVAKALGLELNSKLINTMEGDQLKPEFVRINPQHTIPTLVDNGFVI 65

  Fly    66 ADSHAINSYLVSKYGRNDS-LYPKDLKKRAIVDQRLHYDSSVVTSTGRAITFPLFWENKTEIPQA 129
            .:|.||..|||.|||:.|| |||.|.:|||:::|||::|...:........|.:|...|.. .|.
  Fly    66 WESRAIAVYLVEKYGKPDSPLYPNDPQKRALINQRLYFDMGTLYDALTKYFFLIFRTGKFG-DQE 129

  Fly   130 RIDALEGVYKSLNLFLENGNYLAGDNLTIADFHVIAGLT--GFFVFLPVDATKYPELAAWIKRI- 191
            .:|.:...:..||.|||..:::||..||:||..::|.::  .:|.|   |.:|:|.:..|:|..
  Fly   130 ALDKVNSAFGFLNTFLEGQDFVAGSQLTVADIVILATVSTVEWFSF---DLSKFPNVERWLKNAP 191

  Fly   192 KELPYYEE-----ANGSRAAQIIEFIKSKK 216
            |..|.:|:     ..|.:..|.::..|.|:
  Fly   192 KVTPGWEQNLESLQQGKKFLQDLQAAKEKE 221

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE3	NP_611325.2	GstA	4..195	CDD:223698	75/194 (39%)
		GST_N_Delta_Epsilon	4..77	CDD:239343	33/72 (46%)
		GST_C_Delta_Epsilon	91..208	CDD:198287	35/124 (28%)
GstD7	NP_525114.1	GST_N_Delta_Epsilon	4..77	CDD:239343	33/72 (46%)
		GstA	6..188	CDD:223698	72/185 (39%)
		GST_C_Delta_Epsilon	92..206	CDD:198287	34/117 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45460330
Domainoid	1	1.000	54	1.000	Domainoid score	I4138
eggNOG	1	0.900	-	-		E1_COG0625
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	77	1.000	Inparanoid score	I2398
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1231780at2759
OrthoFinder	1	1.000	-	-		FOG0000035
OrthoInspector	1	1.000	-	-		mtm975
orthoMCL	1	0.900	-	-		OOG6_100130
Panther	1	1.100	-	-	P	PTHR43969
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X30
	11	10.800