DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstE3 and GstD6

DIOPT Version :9

Sequence 1:	NP_611325.2	Gene:	GstE3 / 37108	FlyBaseID:	FBgn0063497	Length:	220	Species:	Drosophila melanogaster
Sequence 2:	NP_524915.1	Gene:	GstD6 / 48339	FlyBaseID:	FBgn0010042	Length:	215	Species:	Drosophila melanogaster

Alignment Length:	217	Identity:	76/217 - (35%)
Similarity:	123/217 - (56%)	Gaps:	14/217 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LTLYGIDGSPPVRSVLLTLRALNLDFDYKIVNLMEKEHLKPEFLKINPLHTVPALDDNGFYLADS 68
            :.||.:.|||..|:|::|.:|:.::|:...||....|.|:|.|:||||.||:|.|.||.|.:.::
  Fly     1 MDLYNMSGSPSTRAVMMTAKAVGVEFNSIQVNTFVGEQLEPWFVKINPQHTIPTLVDNLFVIWET 65

  Fly    69 HAINSYLVSKYGRNDSLYPKDLKKRAIVDQRLHYDSSVVTSTGRAITFPLFWENKTEIP--QARI 131
            .||..|||.:||::|||||||.:|:|:::|||::|...:........|||.   :|..|  |..:
  Fly    66 RAIVVYLVEQYGKDDSLYPKDPQKQALINQRLYFDMGTLYDGIAKYFFPLL---RTGKPGTQENL 127

  Fly   132 DALEGVYKSLNLFLENGNYLAGDNLTIADFHVIAGLTGFFVFLPVDATKYPELAAWIKRIKEL-P 195
            :.|...:..||.||:..:|:||:.|::||. ||.........:..|..|:|.:..|.|..::: |
  Fly   128 EKLNAAFDLLNNFLDGQDYVAGNQLSVADI-VILATVSTTEMVDFDLKKFPNVDRWYKNAQKVTP 191

  Fly   196 YYEEANGSRAAQIIEFIKSKKF 217
            .::|       .:.....:|||
  Fly   192 GWDE-------NLARIQSAKKF 206

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE3	NP_611325.2	GstA	4..195	CDD:223698	71/193 (37%)
		GST_N_Delta_Epsilon	4..77	CDD:239343	31/72 (43%)
		GST_C_Delta_Epsilon	91..208	CDD:198287	32/119 (27%)
GstD6	NP_524915.1	GST_N_Delta_Epsilon	1..74	CDD:239343	31/72 (43%)
		PLN02395	11..208	CDD:166036	71/207 (34%)
		GST_C_Delta_Epsilon	88..204	CDD:198287	32/126 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45460317
Domainoid	1	1.000	54	1.000	Domainoid score	I4138
eggNOG	1	0.900	-	-		E1_COG0625
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	77	1.000	Inparanoid score	I2398
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1231780at2759
OrthoFinder	1	1.000	-	-		FOG0000035
OrthoInspector	1	1.000	-	-		mtm975
orthoMCL	1	0.900	-	-		OOG6_100130
Panther	1	1.100	-	-	P	PTHR43969
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X30
	11	10.800