DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstE3 and GstE12

DIOPT Version :9

Sequence 1:	NP_611325.2	Gene:	GstE3 / 37108	FlyBaseID:	FBgn0063497	Length:	220	Species:	Drosophila melanogaster
Sequence 2:	NP_001246500.1	Gene:	GstE12 / 37960	FlyBaseID:	FBgn0027590	Length:	223	Species:	Drosophila melanogaster

Alignment Length:	216	Identity:	94/216 - (43%)
Similarity:	136/216 - (62%)	Gaps:	1/216 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGKLTLYGIDGSPPVRSVLLTLRALNLDFDYKIVNLMEKEHLKPEFLKINPLHTVPALDDNGFYL 65
            |.|..||....|||.|:||||.:|:.||.:.:.:||::.|||.|||||:||.||:|.|.|....:
  Fly     1 MSKPALYYATLSPPSRAVLLTAKAIGLDLELRPINLLKGEHLTPEFLKLNPQHTIPTLIDGEATI 65

  Fly    66 ADSHAINSYLVSKYGRND-SLYPKDLKKRAIVDQRLHYDSSVVTSTGRAITFPLFWENKTEIPQA 129
            .|||||.:|||.|||:.: .||||:|.:||.||.|||.||..:.:..|.:..|:.:...|:....
  Fly    66 IDSHAICAYLVEKYGQKEQQLYPKELVQRANVDARLHLDSGHLFARLRFLYEPILYYGSTDCSID 130

  Fly   130 RIDALEGVYKSLNLFLENGNYLAGDNLTIADFHVIAGLTGFFVFLPVDATKYPELAAWIKRIKEL 194
            :|..::..::.|..||::..||.|.:||||||..:|.:|......|:|..|:|::.||:||:.||
  Fly   131 KIAYIQKCWEILEGFLKDQPYLCGSDLTIADFCAVATVTSVNDTAPIDEFKFPKMHAWLKRLAEL 195

  Fly   195 PYYEEANGSRAAQIIEFIKSK 215
            |||:|.||..|.::....|:|
  Fly   196 PYYQEVNGDGADELKSIFKAK 216

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE3	NP_611325.2	GstA	4..195	CDD:223698	82/191 (43%)
		GST_N_Delta_Epsilon	4..77	CDD:239343	37/72 (51%)
		GST_C_Delta_Epsilon	91..208	CDD:198287	44/116 (38%)
GstE12	NP_001246500.1	GST_N_Delta_Epsilon	4..77	CDD:239343	37/72 (51%)
		GstA	6..201	CDD:223698	86/194 (44%)
		GST_C_Delta_Epsilon	92..210	CDD:198287	44/117 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468011
Domainoid	1	1.000	54	1.000	Domainoid score	I4138
eggNOG	1	0.900	-	-		E1_COG0625
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	77	1.000	Inparanoid score	I2398
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D118089at33392
OrthoFinder	1	1.000	-	-		FOG0000035
OrthoInspector	1	1.000	-	-		mtm975
orthoMCL	1	0.900	-	-		OOG6_100130
Panther	1	1.100	-	-	P	PTHR43969
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X30
	11	10.800