DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstE3 and gst1

DIOPT Version :9

Sequence 1:	NP_611325.2	Gene:	GstE3 / 37108	FlyBaseID:	FBgn0063497	Length:	220	Species:	Drosophila melanogaster
Sequence 2:	NP_588298.1	Gene:	gst1 / 2538694	PomBaseID:	SPCC191.09c	Length:	229	Species:	Schizosaccharomyces pombe

Alignment Length:	226	Identity:	59/226 - (26%)
Similarity:	97/226 - (42%)	Gaps:	43/226 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGKLTLYGIDGSPPVRSVLLTLRALNLDFDYKIVNLMEKEHLKPEFLKINPLHTVPALDD---NG 62
            |.:.||:.....|....|:..|:.|:|.::.:.||..:.|...||.|.:||...||.|.|   |.
pombe     1 MAQFTLWSHAHGPNPWKVVQALKELDLTYETRYVNFSKNEQKSPEHLALNPNGRVPTLIDHHNND 65

  Fly    63 FYLADSHAINSYLVSKYG--RNDSLYPKDLKKRAIVDQRLHYDSS---VVTSTGRAITFPLFWEN 122
            :.:.:|.||..||..||.  |..|| |:|..:...|.|.|.:.:|   ::  .|:|..|.::.:.
pombe    66 YTIWESDAILIYLADKYDTERKISL-PRDHPEYYKVIQYLFFQASGQGII--WGQAGWFSVYHQE 127

  Fly   123 ---------KTEIPQARIDALEGVYKSLNLFLENGNYLAGDNLTIADFHVIAGLTGFFVFL---- 174
                     :.||.:. :..||.:       |::.:||..:..||||...|: ...|...:
pombe   128 LVISAITRYRNEIKRV-LGVLEDI-------LKDRDYLVANRFTIADLSFIS-WNNFLEIIFAEG 183

  Fly   175 ---------PVDATK-YPELAAWIKRIKELP 195
                     .:|..| :|...:|.:|:...|
pombe   184 KFSIEEEVPQLDFEKEFPRTYSWHQRLLARP 214

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE3	NP_611325.2	GstA	4..195	CDD:223698	57/221 (26%)
		GST_N_Delta_Epsilon	4..77	CDD:239343	25/75 (33%)
		GST_C_Delta_Epsilon	91..208	CDD:198287	26/131 (20%)
gst1	NP_588298.1	GST_N_Ure2p_like	3..84	CDD:239346	27/80 (34%)
		GstA	5..218	CDD:223698	58/222 (26%)
		GST_C_Ure2p	96..219	CDD:198326	26/130 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	54	1.000	Domainoid score	I3221
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	80	1.000	Inparanoid score	I1854
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000035
OrthoInspector	1	1.000	-	-		mtm9258
orthoMCL	1	0.900	-	-		OOG6_100130
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X30
TreeFam	0	0.000	Not matched by this tool.
	9	8.760