DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstE3 and Vars

DIOPT Version :9

Sequence 1:	NP_611325.2	Gene:	GstE3 / 37108	FlyBaseID:	FBgn0063497	Length:	220	Species:	Drosophila melanogaster
Sequence 2:	NP_035820.3	Gene:	Vars / 22321	MGIID:	90675	Length:	1263	Species:	Mus musculus

Alignment Length:	166	Identity:	37/166 - (22%)
Similarity:	59/166 - (35%)	Gaps:	21/166 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 PLHTVPALDD--NGFYLADSHAINSYLVSKYGRNDSLYPKDL------KKRAIVDQRLHYDSSVV 107
            |...:|||:.  .|.::..:.|:...          |:|..|      :...:|.|.:.|..:.:
Mouse    53 PPPRLPALEQGPGGLWVWGAPAVAQL----------LWPAGLGGPGGSRAAVLVQQWVSYADTEL 107

  Fly   108 TSTGRAITFP-LFWENKTEIPQARIDALEGVYKSLNLFLENGNYLAGDNLTIADFHVIAGLTGFF 171
            .......|.| |......:.|||.:.||......|..:|....|||||..|:||...:..|...|
Mouse   108 IPAACGATLPALGLRGPGQDPQAALGALGKALNPLEDWLRLHTYLAGDAPTLADLAAVTALLLPF 172

  Fly   172 VFL--PVDATKYPELAAWIKRIKELPYYEEANGSRA 205
            .::  |.....:..:..|.......|.:....|..|
Mouse   173 RYVLDPSARRIWGNVTRWFNTCVRQPEFRAVLGEVA 208

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE3	NP_611325.2	GstA	4..195	CDD:223698	34/154 (22%)
		GST_N_Delta_Epsilon	4..77	CDD:239343	6/27 (22%)
		GST_C_Delta_Epsilon	91..208	CDD:198287	28/118 (24%)
Vars	NP_035820.3	GST_C_family	92..213	CDD:383119	28/117 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	218..294
		PTZ00419	281..1263	CDD:240411
		'HIGH' region	343..353
		'KMSKS' region	861..865
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810