DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment GstE3 and eef-1G

DIOPT Version :9

Sequence 1:	NP_611325.2	Gene:	GstE3 / 37108	FlyBaseID:	FBgn0063497	Length:	220	Species:	Drosophila melanogaster
Sequence 2:	NP_505800.1	Gene:	eef-1G / 179522	WormBaseID:	WBGene00008920	Length:	398	Species:	Caenorhabditis elegans

Alignment Length:	221	Identity:	52/221 - (23%)
Similarity:	87/221 - (39%)	Gaps:	27/221 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 GKLTLYGIDGSPPVRSVLLTLRALNLDFDYKIVNLMEKEHLKPEFLKINPLHTVPALDDNGFYLA 66
            ||  |||...:...:.||:..:..|     |.|.|........:|    ||...||.:.:.. |.
Worm     3 GK--LYGNKDNFRTQKVLIAAKLAN-----KTVTLAGDAAPADKF----PLGVTPAFEGDAL-LF 55

  Fly    67 DSHAINSYLVSKYGRNDSLYPKDLKKRAIVDQRLHYDSSVVTSTGRAITFPLFWENKTEIPQARI 131
            .:.:|..:|.......:::......:..::...|.|    |..:..|..|     :|..:.|.:
Worm    56 GAESIGLHLTGTSANAETVQWLQFAEGYLLPAVLGY----VLPSVSAANF-----DKKTVEQYK- 110

  Fly   132 DALEGVYKSLNLFLENGNYLAGDNLTIADFHVIAGLTGFFVF-LPVDATK-YPELAAWIKRIKEL 194
            :.|.|..:.|:..|....||.|:.|::||..|...|...|.: |..:|.| ...:..|.:.:...
Worm   111 NELNGQLQVLDRVLVKKTYLVGERLSLADVSVALDLLPAFQYVLDANARKSIVNVTRWFRTVVNQ 175

  Fly   195 PYYEEANG--SRAAQIIEFIKSKKFT 218
            |..:|..|  |.|:.:.:| ...|||
Worm   176 PAVKEVLGEVSLASSVAQF-NQAKFT 200

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE3	NP_611325.2	GstA	4..195	CDD:223698	41/192 (21%)
		GST_N_Delta_Epsilon	4..77	CDD:239343	17/72 (24%)
		GST_C_Delta_Epsilon	91..208	CDD:198287	29/120 (24%)
eef-1G	NP_505800.1	GST_N_EF1Bgamma	3..77	CDD:239342	19/85 (22%)
		GstA	4..181	CDD:223698	43/198 (22%)
		GST_C_EF1Bgamma_like	71..188	CDD:198290	28/126 (22%)
		EF1G	238..343	CDD:279041
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910