DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstE2 and Clic5

DIOPT Version :9

Sequence 1:	NP_611324.1	Gene:	GstE2 / 37107	FlyBaseID:	FBgn0063498	Length:	221	Species:	Drosophila melanogaster
Sequence 2:	NP_446055.1	Gene:	Clic5 / 94272	RGDID:	620659	Length:	251	Species:	Rattus norvegicus

Alignment Length:	169	Identity:	41/169 - (24%)
Similarity:	65/169 - (38%)	Gaps:	53/169 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    81 ANSDELYPR-DLVLRAQVD----------QRLFFDASILFMSLRNVSIPYFLRQVSLVPKEKVDN 134
            ||.|:..|. :|.::|.:|          ||||     :.:.|:.|     :..|:.|      :
  Rat     7 ANGDDRDPEIELFVKAGIDGESIGNCPFSQRLF-----MILWLKGV-----VFNVTTV------D 55

  Fly   135 IKDAYGHLENFLGDN--PYLTGSQLTIADLCCGATASSLAAVLD--LDELKYPKVA--------A 187
            :|.....|.|.....  |:||.:.....|:      :.:...|:  |...||||:|        |
  Rat    56 LKRKPADLHNLAPGTHPPFLTFNGDVKTDV------NKIEEFLEETLTPEKYPKLAARHRESNTA 114

  Fly   188 WFERLSKLPHY-----EEDNL---RGLKKYINLLKPVLN 218
            ..:..||...|     :::|.   |||.|.:..|...||
  Rat   115 GIDIFSKFSAYIKNTKQQNNAALERGLTKALRKLDDYLN 153

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE2	NP_611324.1	GstA	5..196	CDD:223698	32/137 (23%)
		GST_N_Delta_Epsilon	5..78	CDD:239343
		GST_C_Delta_Epsilon	94..209	CDD:198287	32/144 (22%)
Clic5	NP_446055.1	Required for insertion into the membrane. /evidence=ECO:0000250	1..98		24/112 (21%)
Clic5	NP_446055.1	O-ClC	14..249	CDD:129941	38/162 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166348302
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930