DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstE2 and CLIC3

DIOPT Version :9

Sequence 1:	NP_611324.1	Gene:	GstE2 / 37107	FlyBaseID:	FBgn0063498	Length:	221	Species:	Drosophila melanogaster
Sequence 2:	NP_004660.2	Gene:	CLIC3 / 9022	HGNCID:	2064	Length:	236	Species:	Homo sapiens

Alignment Length:	128	Identity:	31/128 - (24%)
Similarity:	42/128 - (32%)	Gaps:	41/128 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    95 AQVDQRLFFDAS-------------ILFMSLRNVSIPYFLRQVSLVPKEKVDNIKDAYGHLENFL 146
            |:...:||..||             .|||.|....:|:.|..|.  .:...|.:||
Human     2 AETKLQLFVKASEDGESVGHCPSCQRLFMVLLLKGVPFTLTTVD--TRRSPDVLKD--------- 55

  Fly   147 GDNPYLTGSQLTIADLCCGATASSLAAVLDLDEL----KYPKVAAWFERLSKLPHYEEDNLRG 205
                :..||||.|......|...:|.....|:|.    .:|.:|         |.|.|.|..|
Human    56 ----FAPGSQLPILLYDSDAKTDTLQIEDFLEETLGPPDFPSLA---------PRYRESNTAG 105

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE2	NP_611324.1	GstA	5..196	CDD:223698	26/117 (22%)
		GST_N_Delta_Epsilon	5..78	CDD:239343
		GST_C_Delta_Epsilon	94..209	CDD:198287	31/128 (24%)
CLIC3	NP_004660.2	Required for insertion into the membrane. /evidence=ECO:0000250	1..88		24/100 (24%)
CLIC3	NP_004660.2	PLN02817	5..229	CDD:330276	30/125 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165154452
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930