DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstE2 and CAM1

DIOPT Version :9

Sequence 1:	NP_611324.1	Gene:	GstE2 / 37107	FlyBaseID:	FBgn0063498	Length:	221	Species:	Drosophila melanogaster
Sequence 2:	NP_015277.1	Gene:	CAM1 / 856059	SGDID:	S000005969	Length:	415	Species:	Saccharomyces cerevisiae

Alignment Length:	191	Identity:	48/191 - (25%)
Similarity:	83/191 - (43%)	Gaps:	19/191 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 LRALNLDYEYKEMDLLAGDHFKDAFLKKNPQHTVPLLEDNGALIWDSHAIVCYLVDKYANSDELY 87
            ::||.||.:....|..|....:|..|||.|....|    .|..:.::.||..||| |.:..|::.
Yeast    21 VKALKLDVKVVTPDAAAEQFARDFPLKKVPAFVGP----KGYKLTEAMAINYYLV-KLSQDDKMK 80

  Fly    88 PR------DLVLRAQVDQRLFFDASILFMSLRNVSIPYFLRQVSLVPKEKVDNIKDAYGHL---- 142
            .:      ||..:||:.:......|.|.:.:.|..:|  |:..:...|:.||:..||...:
Yeast    81 TQLLGADDDLNAQAQIIRWQSLANSDLCIQIANTIVP--LKGGAPYNKKSVDSAMDAVDKIVDIF 143

  Fly   143 ENFLGDNPYLTGSQLTIADLCCGATASSLAAVLDLDE--LKYPKVAAWFERLSKLPHYEED 201
            ||.|.:..||....:::|||...:..:.....|...|  .::|.:..||..:...|..:::
Yeast   144 ENRLKNYTYLATENISLADLVAASIFTRYFESLFGTEWRAQHPAIVRWFNTVRASPFLKDE 204

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE2	NP_611324.1	GstA	5..196	CDD:223698	47/184 (26%)
		GST_N_Delta_Epsilon	5..78	CDD:239343	17/54 (31%)
		GST_C_Delta_Epsilon	94..209	CDD:198287	26/114 (23%)
CAM1	NP_015277.1	GST_N_EF1Bgamma	4..73	CDD:239342	18/56 (32%)
		GST_C_EF1Bgamma_like	92..214	CDD:198290	26/115 (23%)
		EF1G	255..359	CDD:395522
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157345094
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740