DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstE2 and GstD9

DIOPT Version :9

Sequence 1:	NP_611324.1	Gene:	GstE2 / 37107	FlyBaseID:	FBgn0063498	Length:	221	Species:	Drosophila melanogaster
Sequence 2:	NP_001287303.1	Gene:	GstD9 / 41502	FlyBaseID:	FBgn0038020	Length:	218	Species:	Drosophila melanogaster

Alignment Length:	219	Identity:	87/219 - (39%)
Similarity:	119/219 - (54%)	Gaps:	9/219 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 LVLYGMDISPPVRACKLTLRALNLDYEYKEMDLLAGDHFKDAFLKKNPQHTVPLLEDNGALIWDS 69
            |..|.|..|.|.|:..:|.|||.|:...|::||.||:|.|..|:|.|||||:|.|.|:|..||:|
  Fly     2 LDFYYMLYSAPCRSILMTARALGLELNKKQVDLDAGEHLKPEFVKINPQHTIPTLVDDGFAIWES 66

  Fly    70 HAIVCYLVDKYANSDELYPRDLVLRAQVDQRLFFDASILFMSLRNVSIPYFLRQVSLVPKEKVDN 134
            .||:.||.:||.....|||:|...||.::||||||.|.|:.|......|.....|. .|.:. ||
  Fly    67 RAILIYLAEKYDKDGSLYPKDPQQRAVINQRLFFDLSTLYQSYVYYYYPQLFEDVK-KPADP-DN 129

  Fly   135 IK---DAYGHLENFLGDNPYLTGSQLTIADLCCGATASSLAAVLDLDELKYPKVAAWFERLSK-L 195
            :|   ||:......|....|...::||:||....||.|:. .:.:.|..|||:|..|::...| :
  Fly   130 LKKIDDAFAMFNTLLKGQQYAALNKLTLADFALLATVSTF-EISEYDFGKYPEVVRWYDNAKKVI 193

  Fly   196 PHYEEDNLRGLKKYINL-LKPVLN 218
            |.:|| |..|.:.|..| |..:||
  Fly   194 PGWEE-NWEGCEYYKKLYLGAILN 216

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE2	NP_611324.1	GstA	5..196	CDD:223698	77/194 (40%)
		GST_N_Delta_Epsilon	5..78	CDD:239343	36/72 (50%)
		GST_C_Delta_Epsilon	94..209	CDD:198287	40/118 (34%)
GstD9	NP_001287303.1	GST_N_Delta_Epsilon	2..75	CDD:239343	36/72 (50%)
		GstA	4..187	CDD:223698	75/185 (41%)
		GST_C_Delta_Epsilon	89..207	CDD:198287	40/121 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45460293
Domainoid	1	1.000	54	1.000	Domainoid score	I4138
eggNOG	1	0.900	-	-		E1_COG0625
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	77	1.000	Inparanoid score	I2398
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1231780at2759
OrthoFinder	1	1.000	-	-		FOG0000035
OrthoInspector	1	1.000	-	-		mtm975
orthoMCL	1	0.900	-	-		OOG6_103768
Panther	1	1.100	-	-	P	PTHR43969
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X30
	11	10.800