DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstE2 and GstE14

DIOPT Version :9

Sequence 1:	NP_611324.1	Gene:	GstE2 / 37107	FlyBaseID:	FBgn0063498	Length:	221	Species:	Drosophila melanogaster
Sequence 2:	NP_610855.1	Gene:	GstE14 / 36467	FlyBaseID:	FBgn0033817	Length:	232	Species:	Drosophila melanogaster

Alignment Length:	225	Identity:	68/225 - (30%)
Similarity:	118/225 - (52%)	Gaps:	26/225 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 KLVLYGMDISPPVRACKLTLRALNLDYEYKEMDLLAGDHFKDAFLKKNPQHTVPLLEDNGALIWD 68
            |.:||..:.|||||:|.:.::.|::|.|.:.::|..|:.|:..||..||||:||.|.....::.|
  Fly     5 KPILYYDERSPPVRSCLMLIKLLDIDVELRFVNLFKGEQFQKDFLALNPQHSVPTLVHGDLVLTD 69

  Fly    69 SHAIVCYLVDKYANSDELYPRDLVLRAQVDQRLFFDASILF------------MSLRNVSIPYFL 121
            ||||:.:|.:|:.....|:|::...|.:|...|.|:.|.||            ....||.:.:..
  Fly    70 SHAILIHLAEKFDEGGSLWPQEHAERMKVLNLLLFECSFLFRRDSDFMSATVRQGFANVDVAHHE 134

  Fly   122 RQVSLVPKEKVDNIKDAYGHLENFLGDNPYLTGSQLTIADLCCGATASSLAAVLDLDELKYPKVA 186
            |:::           :||..:|.:|.::.::.|.|||:|||....|.|::..:..|.:  :|::.
  Fly   135 RKLT-----------EAYIIMERYLENSDFMAGPQLTLADLSIVTTLSTVNLMFPLSQ--FPRLR 186

  Fly   187 AWFERLSKLPHYEEDNLRGLKKYINLLKPV 216
            .||..:.:|..||. |..||:|....::.|
  Fly   187 RWFTAMQQLDAYEA-NCSGLEKLRQTMESV 215

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE2	NP_611324.1	GstA	5..196	CDD:223698	59/202 (29%)
		GST_N_Delta_Epsilon	5..78	CDD:239343	29/72 (40%)
		GST_C_Delta_Epsilon	94..209	CDD:198287	33/126 (26%)
GstE14	NP_610855.1	GstA	6..200	CDD:223698	61/206 (30%)
		GST_N_Delta_Epsilon	6..79	CDD:239343	29/72 (40%)
		GST_C_Delta_Epsilon	94..209	CDD:198287	34/128 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	54	1.000	Domainoid score	I4138
eggNOG	1	0.900	-	-		E1_COG0625
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	77	1.000	Inparanoid score	I2398
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1231780at2759
OrthoFinder	1	1.000	-	-		FOG0000035
OrthoInspector	1	1.000	-	-		mtm975
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR43969
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X30
	9	8.970