DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment GstE2 and clic1

DIOPT Version :9

Sequence 1:	NP_611324.1	Gene:	GstE2 / 37107	FlyBaseID:	FBgn0063498	Length:	221	Species:	Drosophila melanogaster
Sequence 2:	NP_997847.1	Gene:	clic1 / 324481	ZFINID:	ZDB-GENE-030131-3202	Length:	241	Species:	Danio rerio

Alignment Length:	166	Identity:	41/166 - (24%)
Similarity:	64/166 - (38%)	Gaps:	52/166 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    83 SDELYPRDLVLRAQVD----------QRLFFDASILFMSLRNVSIPYFLRQVSLVP-KEKVDNIK 136
            |:|....:|.::|..|          ||||     :.:.|:.|:.     .|:.|. |.|.:.:|
Zfish     2 SEEKPEVELFVKAGSDGQSIGNCPFSQRLF-----MVLWLKGVTF-----NVTTVDMKRKPEILK 56

  Fly   137 D-AYGHLENFLGDNPYLTGSQLTIADLCCGATASSLAAVLD--LDELKYPKVA--------AWFE 190
            | |.|....||     |.|:::.       ...:.:...|:  |...|||::|        |..:
Zfish    57 DLAPGAQPPFL-----LYGTEVK-------TDTNKIEEFLEETLCPPKYPRLAACNPESNTAGLD 109

  Fly   191 RLSKLPHY-------EEDNL-RGLKKYINLLKPVLN 218
            ..||...|       ..||| :||.|.:..|...|:
Zfish   110 VFSKFSAYIKNSNPQMNDNLEKGLLKALKKLDDYLS 145

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE2	NP_611324.1	GstA	5..196	CDD:223698	32/134 (24%)
		GST_N_Delta_Epsilon	5..78	CDD:239343
		GST_C_Delta_Epsilon	94..209	CDD:198287	35/144 (24%)
clic1	NP_997847.1	GST_N_CLIC	3..93	CDD:239359	24/111 (22%)
		O-ClC	6..241	CDD:129941	39/162 (24%)
		GST_C_CLIC1	100..238	CDD:198333	12/46 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170589701
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930