DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstE2 and Clic6

DIOPT Version :9

Sequence 1:	NP_611324.1	Gene:	GstE2 / 37107	FlyBaseID:	FBgn0063498	Length:	221	Species:	Drosophila melanogaster
Sequence 2:	NP_788267.2	Gene:	Clic6 / 304081	RGDID:	727938	Length:	613	Species:	Rattus norvegicus

Alignment Length:	215	Identity:	43/215 - (20%)
Similarity:	72/215 - (33%)	Gaps:	91/215 - (42%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSDKLVLYGMDISPPVRACKLTLRALNLDYEYKEMDLLAGDHFK--DAFLKKNPQHTVPLLEDNG 63
            :.:|||       ||        |...|..::.|.:....|.|.  .||:|...:
  Rat   456 LEEKLV-------PP--------RYPKLGTQHPESNSAGNDVFAKFSAFIKNTKK---------- 495

  Fly    64 ALIWDSHAIVCYLVDKYANSDELYPRDLVLRA--QVDQRLFFDASILFMSLRNVSIPYFLRQVSL 126
                              :::::|.::| |||  ::|..|            |..:|
  Rat   496 ------------------DANDIYEKNL-LRALKKLDSYL------------NSPLP-------- 521

  Fly   127 VPKEKVDNIKDAYGHLENFLGDNPYLTGSQLTIADLCCGATASSLAAVLDLDELKYPKVAAWFER 191
                  |.| |||...:..:....:|.|.:||:||  |..          |.:|...|:.|...|
  Rat   522 ------DEI-DAYSTEDVTVSQRKFLDGDELTLAD--CNL----------LPKLHIIKIVAKKYR 567

  Fly   192 LSKLPHYEEDNLRGLKKYIN 211
            ..:.|    ..:.|:.:|:|
  Rat   568 GFEFP----SEMTGIWRYLN 583

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE2	NP_611324.1	GstA	5..196	CDD:223698	38/194 (20%)
		GST_N_Delta_Epsilon	5..78	CDD:239343	12/74 (16%)
		GST_C_Delta_Epsilon	94..209	CDD:198287	25/116 (22%)
Clic6	NP_788267.2	2A1904	<51..318	CDD:273344
Clic6	NP_788267.2	O-ClC	380..613	CDD:129941	43/215 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166348026
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930