DRSC/TRiP Functional Genomics Resources

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Protein Alignment GstE2 and CLIC1

DIOPT Version :9

Sequence 1:NP_611324.1 Gene:GstE2 / 37107 FlyBaseID:FBgn0063498 Length:221 Species:Drosophila melanogaster
Sequence 2:NP_001274522.1 Gene:CLIC1 / 1192 HGNCID:2062 Length:241 Species:Homo sapiens


Alignment Length:211 Identity:51/211 - (24%)
Similarity:73/211 - (34%) Gaps:70/211 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly     6 VLYGMDISP--------------PVRACKLTLRALNLDYEYKEMDLLAGDHFKDAFLKKNPQHTV 56
            :|||.::..              |.|..||.  |||.:.....:|:.|  .| .|::|    ::.
Human    67 LLYGTEVHTDTNKIEEFLEAVLCPPRYPKLA--ALNPESNTAGLDIFA--KF-SAYIK----NSN 122

  Fly    57 PLLEDN---GALIWDSHAIVCYLVDKYANS------DELYPRDLVLRAQVDQRLFFDASILFMSL 112
            |.|.||   |.|      ....::|.|..|      ||....|    ..|.||.|.|.:.|    
Human   123 PALNDNLEKGLL------KALKVLDNYLTSPLPEEVDETSAED----EGVSQRKFLDGNEL---- 173

  Fly   113 RNVSIPYFLRQVSLVPKEKVDNI--KDAYGHL--ENFLGDNPYLTGSQLTIADLCCGATASSLAA 173
                   .|...:|:||..:..:  |...|..  |.|.|.:.||:.:.          .....|:
Human   174 -------TLADCNLLPKLHIVQVVCKKYRGFTIPEAFRGVHRYLSNAY----------AREEFAS 221

  Fly   174 VLDLD---ELKYPKVA 186
            ....|   ||.|.:||
Human   222 TCPDDEEIELAYEQVA 237

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GstE2NP_611324.1 GstA 5..196 CDD:223698 51/211 (24%)
GST_N_Delta_Epsilon 5..78 CDD:239343 21/88 (24%)
GST_C_Delta_Epsilon 94..209 CDD:198287 24/100 (24%)
CLIC1NP_001274522.1 Required for insertion into the membrane 2..90 3/22 (14%)
O-ClC 6..241 CDD:129941 51/211 (24%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165154544
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.930

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