DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstE1 and TEF4

DIOPT Version :9

Sequence 1:	NP_611323.1	Gene:	GstE1 / 37106	FlyBaseID:	FBgn0034335	Length:	224	Species:	Drosophila melanogaster
Sequence 2:	NP_012842.1	Gene:	TEF4 / 853781	SGDID:	S000001564	Length:	412	Species:	Saccharomyces cerevisiae

Alignment Length:	197	Identity:	42/197 - (21%)
Similarity:	85/197 - (43%)	Gaps:	39/197 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 KLTLKVLNLDYEYKEVNLQAGEHLSEEYVKKNPQHTVPMLDDNGTFIWDSHAIAAYLVDKYAKSD 85
            ||.:|:::|:        |:.|..|...:|:.|    ..|...|..:.::.||..||.::.|...
Yeast    25 KLDVKIVDLE--------QSSEFASLFPLKQAP----AFLGPKGLKLTEALAIQFYLANQVADEK 77

  Fly    86 E---LYPKDLAKRAIVNQRLFFDASVIYASIA------NVSRPFW-INGVTEVPQEKLDA----V 136
            |   |...|:.:::.:         :.:||:|      |::|||. ..|:....::.:||    :
Yeast    78 ERARLLGSDVIEKSQI---------LRWASLANSDVMSNIARPFLSFKGLIPYNKKDVDACFVKI 133

  Fly   137 HQGLKLLETFLGNSPYLAGDSLTLADLSTGPTVSAVPAAVDIDP---ATYPKVTAWLDRLNKLPY 198
            .....:.:..|.:..::|.::::|.||....: .|...|..:.|   |.:|.:..|.:.:...|.
Yeast   134 DNLAAVFDARLRDYTFVATENISLGDLHAAGS-WAFGLATILGPEWRAKHPHLMRWFNTVAASPI 197

  Fly   199 YK 200
            .|
Yeast   198 VK 199

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE1	NP_611323.1	GST_N_Delta_Epsilon	6..79	CDD:239343	15/57 (26%)
		GstA	8..197	CDD:223698	40/192 (21%)
		GST_C_Delta_Epsilon	94..210	CDD:198287	23/121 (19%)
TEF4	NP_012842.1	GST_N_EF1Bgamma	4..72	CDD:239342	15/58 (26%)
		GST_C_EF1Bgamma_like	89..211	CDD:198290	23/121 (19%)
		EF1G	253..356	CDD:395522
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157345111
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740