DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstE1 and clic3

DIOPT Version :9

Sequence 1:	NP_611323.1	Gene:	GstE1 / 37106	FlyBaseID:	FBgn0034335	Length:	224	Species:	Drosophila melanogaster
Sequence 2:	NP_955818.1	Gene:	clic3 / 84040	ZFINID:	ZDB-GENE-010507-2	Length:	239	Species:	Danio rerio

Alignment Length:	171	Identity:	40/171 - (23%)
Similarity:	65/171 - (38%)	Gaps:	38/171 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 PQHTVPMLDDNGTFIWDSHAIAAYLVDKYAKSDELYPKDLAKRAIVNQRLFFDASVIYASIANVS 117
            |....|.|..||....|::.|..:|.|..|...  |||...:....|..   ...:.:...|.:.
Zfish    59 PGSQPPFLIYNGEVRTDTNKIEEFLEDTLAPPQ--YPKLCCRYKESNTA---GDDIFHKFSAYIK 118

  Fly   118 RPFWIN-GVTEVPQEKLDAVHQGLKLLETFLGNSP---------------YLAGDSLTLADLSTG 166
            .|   | |:.::.::|.  :...:||.:..|...|               ||.|::|:|||.:..
Zfish   119 NP---NPGLNDMLEKKF--LKSLMKLDQYLLTPLPHELDQNPELSTSTRHYLDGNALSLADCNLL 178

  Fly   167 PTVSAVPA------AVDIDPATYPKVTAWLDRLNKLPYYKE 201
            |.:..|..      ..:| ||....::.:||:.     |||
Zfish   179 PKLHIVKVVCKKYRGFEI-PAELKGLSKYLDKA-----YKE 213

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE1	NP_611323.1	GST_N_Delta_Epsilon	6..79	CDD:239343	8/25 (32%)
		GstA	8..197	CDD:223698	37/165 (22%)
		GST_C_Delta_Epsilon	94..210	CDD:198287	27/130 (21%)
clic3	NP_955818.1	GST_N_CLIC	3..92	CDD:239359	10/34 (29%)
		O-ClC	6..237	CDD:129941	40/171 (23%)
		GST_C_CLIC3	99..231	CDD:198332	27/129 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170589617
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930