DRSC/TRiP Functional Genomics Resources

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Protein Alignment GstE1 and GDAP1

DIOPT Version :9

Sequence 1:NP_611323.1 Gene:GstE1 / 37106 FlyBaseID:FBgn0034335 Length:224 Species:Drosophila melanogaster
Sequence 2:NP_061845.2 Gene:GDAP1 / 54332 HGNCID:15968 Length:358 Species:Homo sapiens


Alignment Length:232 Identity:47/232 - (20%)
Similarity:77/232 - (33%) Gaps:70/232 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly     6 IVLYGTDLSPCVRTVKLTLKVLNLDYEYKEVNLQAGEHLSEEYVKKNPQHTVPMLDDNGTFIWDS 70
            ::||....|...:.|:|.:....|..|..:|:|...||....:::.|....||:|......|.::
Human    26 LILYHWTHSFSSQKVRLVIAEKALKCEEHDVSLPLSEHNEPWFMRLNSTGEVPVLIHGENIICEA 90

  Fly    71 HAIAAYLVDKYA----------KSDELYPKDLAKR--------------AIVNQRLFFDASV--- 108
            ..|..||...:.          |....||:....|              .|::..|..|:.:   
Human    91 TQIIDYLEQTFLDERTPRLMPDKESMYYPRVQHYRELLDSLPMDAYTHGCILHPELTVDSMIPAY 155

  Fly   109 ----IYASIANVS-------------RPFWINGVTEVPQEKLDAVHQGLKLLETFL--------- 147
                |.:.|.|..             :..:|.....:..:.||  |..:|.|:..|         
Human   156 ATTRIRSQIGNTESELKKLAEENPDLQEAYIAKQKRLKSKLLD--HDNVKYLKKILDELEKVLDQ 218

  Fly   148 ---------------GNSPYLAGDSLTLADLSTGPTV 169
                           |..|:|.|:|.||||:|...|:
Human   219 VETELQRRNEETPEEGQQPWLCGESFTLADVSLAVTL 255

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GstE1NP_611323.1 GST_N_Delta_Epsilon 6..79 CDD:239343 19/72 (26%)
GstA 8..197 CDD:223698 47/230 (20%)
GST_C_Delta_Epsilon 94..210 CDD:198287 25/134 (19%)
GDAP1NP_061845.2 GST_N_GDAP1 26..98 CDD:239350 18/71 (25%)
GST_C_GDAP1 179..289 CDD:198336 18/79 (23%)
Required for mitochondrial localization 320..358
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165154575
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.930

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