DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment GstE1 and CLIC6

DIOPT Version :9

Sequence 1:NP_611323.1 Gene:GstE1 / 37106 FlyBaseID:FBgn0034335 Length:224 Species:Drosophila melanogaster
Sequence 2:XP_016883895.1 Gene:CLIC6 / 54102 HGNCID:2065 Length:735 Species:Homo sapiens


Alignment Length:178 Identity:44/178 - (24%)
Similarity:64/178 - (35%) Gaps:55/178 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly    17 VRTVKLTLKVLNLDYEYKEVNLQAGEHLSEEYVKKNPQHTVPMLDDNGTFIWDSHAIAAYLVDKY 81
            |.||.|..|..:|.      ||..|         .||    |.:..:|....|.:.|..:|.:|.
Human   488 VTTVDLKRKPADLQ------NLAPG---------TNP----PFMTFDGEVKTDVNKIEEFLEEKL 533

  Fly    82 AKSDELYPKDLAKRAIVNQR---LFFDASVIYASIANVSRPFWINGVTEVPQEKLDAVHQGLKLL 143
            |  ...|||...:....|..   :|...|   |.|.|..:     ...|:.::.|   .:.|:.|
Human   534 A--PPRYPKLGTQHPESNSAGNDVFAKFS---AFIKNTKK-----DANEIHEKNL---LKALRKL 585

  Fly   144 ETFLGNSP-------------------YLAGDSLTLADLSTGPTVSAV 172
            :.:| |||                   :|.||.|||||.:..|.:..:
Human   586 DNYL-NSPLPDEIDAYSTEDVTVSGRKFLDGDELTLADCNLLPKLHII 632

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GstE1NP_611323.1 GST_N_Delta_Epsilon 6..79 CDD:239343 16/61 (26%)
GstA 8..197 CDD:223698 44/178 (25%)
GST_C_Delta_Epsilon 94..210 CDD:198287 23/101 (23%)
CLIC6XP_016883895.1 None


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165154382
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.930

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