DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstE1 and GstE5

DIOPT Version :9

Sequence 1:	NP_611323.1	Gene:	GstE1 / 37106	FlyBaseID:	FBgn0034335	Length:	224	Species:	Drosophila melanogaster
Sequence 2:	NP_611327.1	Gene:	GstE5 / 37110	FlyBaseID:	FBgn0063495	Length:	222	Species:	Drosophila melanogaster

Alignment Length:	212	Identity:	105/212 - (49%)
Similarity:	147/212 - (69%)	Gaps:	1/212 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 IVLYGTDLSPCVRTVKLTLKVLNLDYEYKEVNLQAGEHLSEEYVKKNPQHTVPMLDDNGTFIWDS 70
            :.|||.:.||.||.|||||..|.|.||:..||:...|.|||||:||||:||||.|:|:|.:||||
  Fly     4 LTLYGVNPSPPVRAVKLTLAALQLPYEFVNVNISGQEQLSEEYLKKNPEHTVPTLEDDGNYIWDS 68

  Fly    71 HAIAAYLVDKYAKSDELYPKDLAKRAIVNQRLFFDASVIYAS-IANVSRPFWINGVTEVPQEKLD 134
            |||.||||.|||.||.|||:||.:||:|:|||.|:..|::|: |..:::|.:.||:..:|:|:.|
  Fly    69 HAIIAYLVSKYADSDALYPRDLLQRAVVDQRLHFETGVVFANGIKAITKPLFFNGLNRIPKERYD 133

  Fly   135 AVHQGLKLLETFLGNSPYLAGDSLTLADLSTGPTVSAVPAAVDIDPATYPKVTAWLDRLNKLPYY 199
            |:.:....:||||....|:|||.||:||.|...:::::.|.|:||...||::..|:.||.|||||
  Fly   134 AIVEIYDFVETFLAGHDYIAGDQLTIADFSLISSITSLVAFVEIDRLKYPRIIEWVRRLEKLPYY 198

  Fly   200 KEINEAPAQSYVAFLRS 216
            :|.|...|:.....|:|
  Fly   199 EEANAKGARELETILKS 215

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE1	NP_611323.1	GST_N_Delta_Epsilon	6..79	CDD:239343	45/72 (63%)
		GstA	8..197	CDD:223698	96/189 (51%)
		GST_C_Delta_Epsilon	94..210	CDD:198287	47/116 (41%)
GstE5	NP_611327.1	GstA	4..196	CDD:223698	96/191 (50%)
		Thioredoxin_like	4..77	CDD:294274	45/72 (63%)
		GST_C_Delta_Epsilon	91..209	CDD:198287	47/117 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45467975
Domainoid	1	1.000	54	1.000	Domainoid score	I4138
eggNOG	1	0.900	-	-		E1_COG0625
Homologene	1	1.000	-	-		H120001
Inparanoid	1	1.050	77	1.000	Inparanoid score	I2398
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D118089at33392
OrthoFinder	1	1.000	-	-		FOG0000035
OrthoInspector	1	1.000	-	-		mtm975
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR43969
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X30
	11	10.900