Protein Alignment GstE1 and GSTA4

DIOPT Version :10

• Sequence 1: NP_611323.1
• Gene: GstE1 / 37106
• FlyBaseID: FBgn0034335
• Length: 224
• Species: Drosophila melanogaster
• Sequence 2: NP_001503.1
• Gene: GSTA4 / 2941
• HGNCID: 4629
• Length: 222
• Species: Homo sapiens
• Alignment Length: 207
• Identity: 42/207 - (20%)
• Similarity: 88/207 - (42%)
• Gaps: 43/207 - (20%)

  Fly    27 LNLDYEYKEV-----NLQAGEHLSEEYVKKNPQHTVPMLDDNGTFIWDSHAIAAYLVDKYAKSDE 86
            :..|.|:.|.     .||.|.||..:        .|||::.:|..:..:.:|..|:.||:    .
Human    28 VEFDEEFLETKEQLYKLQDGNHLLFQ--------QVPMVEIDGMKLVQTRSILHYIADKH----N 80

  Fly    87 LYPKDLAKRAIVNQRLFFDASVIYASIANVSRPFWINGVTEVPQEKLDAVHQGLKLLETFL---- 147
            |:.|:|.:|.:::  ::.:.::....:. :..||     .:...::.:.|:...|.:..:.
Human    81 LFGKNLKERTLID--MYVEGTLDLLELL-IMHPF-----LKPDDQQKEVVNMAQKAIIRYFPVFE 137

  Fly   148 ------GNSPYLAGDSLTLADLSTGPTVSAVPAAVDIDPATYPKVTAWLDRLNKLPYYKEINE-- 204
                  |.| :|.|:.|:|||:....|:.|:...:....:.:|.:..:..:|:.:|..|...|
Human   138 KILRGHGQS-FLVGNQLSLADVILLQTILALEEKIPNILSAFPFLQEYTVKLSNIPTIKRFLEPG 201

  Fly   205 -----APAQSYV 211
                 .|.:.||
Human   202 SKKKPPPDEIYV 213

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GstE1	NP_611323.1	GstA	6..201	CDD:440390	37/188 (20%)
GSTA4	NP_001503.1	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold	4..82	CDD:469754	16/65 (25%)
		GST_C_Alpha	86..220	CDD:198317	24/137 (18%)