DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstE1 and EEF1G

DIOPT Version :9

Sequence 1:	NP_611323.1	Gene:	GstE1 / 37106	FlyBaseID:	FBgn0034335	Length:	224	Species:	Drosophila melanogaster
Sequence 2:	NP_001395.1	Gene:	EEF1G / 1937	HGNCID:	3213	Length:	437	Species:	Homo sapiens

Alignment Length:	170	Identity:	38/170 - (22%)
Similarity:	78/170 - (45%)	Gaps:	28/170 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 EYVKKNPQHTVPMLD-DNGTFIWDSHAIAAYLVDKYAKSDELYPKDLAKRAIVNQRLFFDASVIY 110
            |:::|.|...||..: |:|..:::|:|||.|:.::..:...  |:..|:  :|....|.|:.::.
Human    48 EFLRKFPAGKVPAFEGDDGFCVFESNAIAYYVSNEELRGST--PEAAAQ--VVQWVSFADSDIVP 108

  Fly   111 ASIANVSRPFWI----------NGVTEVPQEKLDAVHQGLKLLETFLGNSPYLAGDSLTLADLST 165
            .:..      |:          ...||..:|:   |.:.|.||:.:|....:|.|:.:||||::.
Human   109 PAST------WVFPTLGIMHHNKQATENAKEE---VRRILGLLDAYLKTRTFLVGERVTLADITV 164

  Fly   166 GPTVSAVPAAVDIDPA---TYPKVTAWLDRLNKLPYYKEI 202
            ..|:..:...| ::|:   .:|....|.......|.::.:
Human   165 VCTLLWLYKQV-LEPSFRQAFPNTNRWFLTCINQPQFRAV 203

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE1	NP_611323.1	GST_N_Delta_Epsilon	6..79	CDD:239343	12/32 (38%)
		GstA	8..197	CDD:223698	37/163 (23%)
		GST_C_Delta_Epsilon	94..210	CDD:198287	24/122 (20%)
EEF1G	NP_001395.1	GST_N_EF1Bgamma	4..82	CDD:239342	12/33 (36%)
		GST_C_EF1Bgamma_like	91..213	CDD:198290	25/125 (20%)
		tolA	<212..>278	CDD:236545
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	221..268
		EF1G	277..381	CDD:395522
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810