Protein Alignment GstE10 and CLIC3

DIOPT Version :10

• Sequence 1: NP_611322.1
• Gene: GstE10 / 37105
• FlyBaseID: FBgn0063499
• Length: 240
• Species: Drosophila melanogaster
• Sequence 2: NP_004660.2
• Gene: CLIC3 / 9022
• HGNCID: 2064
• Length: 236
• Species: Homo sapiens
• Alignment Length: 242
• Identity: 55/242 - (22%)
• Similarity: 83/242 - (34%)
• Gaps: 81/242 - (33%)

  Fly    13 PPVRAVLLTLRALQLDHEFHTLDMQAGDHLKPDMLRK-NPQHTVPMLEDGESCIWDSHAIIGYLV 76
            |..:.:.:.|....:.....|:|.:.    .||:|:. .|...:|:|      ::||.|....|.
Human    23 PSCQRLFMVLLLKGVPFTLTTVDTRR----SPDVLKDFAPGSQLPIL------LYDSDAKTDTLQ 77

  Fly    77 NKYAQSDELYPKDPLKRAVVDQRLHFETGVLFH---------------GIFKQLQRALFKENATE 126
            .:....:.|.|.|....|...:..:.....:||               .:::||.||
Human    78 IEDFLEETLGPPDFPSLAPRYRESNTAGNDVFHKFSAFIKNPVPAQDEALYQQLLRA-------- 134

  Fly   127 VPKDRLAELKDAY--ALLEQFLAENP--------YVAGPQLTIADFS------IVATVSTLHLSY 175
                 ||.| |:|  |.||..||..|        ::.|.:||:||.|      ||.||.. |...
Human   135 -----LARL-DSYLRAPLEHELAGEPQLRESRRRFLDGDRLTLADCSLLPKLHIVDTVCA-HFRQ 192

  Fly   176 CPVDATKYPKLSAWLARISALPFYEEDNLRGARLLADKIRSKLPKQF 222
            .|:.|                      .|||.|...|....:  |:|
Human   193 APIPA----------------------ELRGVRRYLDSAMQE--KEF 215

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GstE10	NP_611322.1	GST_N_Delta_Epsilon	4..77	CDD:239343	14/64 (22%)
		GST_C_Delta_Epsilon	91..211	CDD:198287	35/150 (23%)
CLIC3	NP_004660.2	Required for insertion into the membrane. /evidence=ECO:0000250	1..88		15/74 (20%)
		O-ClC	5..229	CDD:129941	55/242 (23%)
		G-site. /evidence=ECO:0000305|PubMed:28198360, ECO:0000305|PubMed:37759794	22..25		1/1 (100%)