DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstE10 and GstD8

DIOPT Version :9

Sequence 1:	NP_001286570.1	Gene:	GstE10 / 37105	FlyBaseID:	FBgn0063499	Length:	240	Species:	Drosophila melanogaster
Sequence 2:	NP_524916.1	Gene:	GstD8 / 48341	FlyBaseID:	FBgn0010044	Length:	212	Species:	Drosophila melanogaster

Alignment Length:	208	Identity:	75/208 - (36%)
Similarity:	117/208 - (56%)	Gaps:	8/208 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 SPPVRAVLLTLRALQLDHEFHTLDMQAGDHLKPDMLRKNPQHTVPMLEDGESCIWDSHAIIGYLV 76
            |.|.|:|::|.:||.:|.....|.:..|:.|||:.::.||||.:|.|.|....||:|.||:.|||
  Fly     9 SAPCRSVIMTAKALGVDLNMKLLKVMDGEQLKPEFVKLNPQHCIPTLVDDGFSIWESRAILIYLV 73

  Fly    77 NKYAQSDELYPKDPLKRAVVDQRLHFETGVLFHGIFKQLQRALFKENATEVPKD--RLAELKDAY 139
            .||...|.|||.||.|:|||:|||:|:.|.||....:    |::.:.....|.|  .:.::..|:
  Fly    74 EKYGADDSLYPSDPQKKAVVNQRLYFDMGTLFQSFVE----AIYPQIRNNHPADPEAMQKVDSAF 134

  Fly   140 ALLEQFLAENPYVAGPQLTIADFSIVATVSTLHLSYCPVDATKYPKLSAWLARISALPFYEEDNL 204
            ..|:.||.:..||||..|||||.:::|:|||..:  ...|..:||.::.|......:....|:|.
  Fly   135 GHLDTFLEDQEYVAGDCLTIADIALLASVSTFEV--VDFDIAQYPNVARWYENAKEVTPGWEENW 197

  Fly   205 RGARLLADKIRSK 217
            .|.:|:...::.:
  Fly   198 DGVQLIKKLVQER 210

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE10	NP_001286570.1	GstA	4..197	CDD:223698	71/186 (38%)
		GST_N_Delta_Epsilon	4..77	CDD:239343	27/64 (42%)
		GST_C_Delta_Epsilon	91..211	CDD:198287	39/121 (32%)
GstD8	NP_524916.1	GstA	1..188	CDD:223698	71/184 (39%)
		GST_N_Delta_Epsilon	1..74	CDD:239343	27/64 (42%)
		GST_C_Delta_Epsilon	88..204	CDD:198287	39/121 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45460262
Domainoid	1	1.000	54	1.000	Domainoid score	I4138
eggNOG	1	0.900	-	-		E1_COG0625
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	77	1.000	Inparanoid score	I2398
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D118089at33392
OrthoFinder	1	1.000	-	-		FOG0000035
OrthoInspector	1	1.000	-	-		mtm975
orthoMCL	1	0.900	-	-		OOG6_100130
Panther	1	1.100	-	-	P	PTHR43969
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X30
	11	10.800