DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstE10 and GstD6

DIOPT Version :9

Sequence 1:	NP_001286570.1	Gene:	GstE10 / 37105	FlyBaseID:	FBgn0063499	Length:	240	Species:	Drosophila melanogaster
Sequence 2:	NP_524915.1	Gene:	GstD6 / 48339	FlyBaseID:	FBgn0010042	Length:	215	Species:	Drosophila melanogaster

Alignment Length:	221	Identity:	83/221 - (37%)
Similarity:	126/221 - (57%)	Gaps:	16/221 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LYGTESSPPVRAVLLTLRALQLDHEFHTLDMQ--AGDHLKPDMLRKNPQHTVPMLEDGESCIWDS 68
            ||....||..|||::|.:|:.:  ||:::.:.  .|:.|:|..::.|||||:|.|.|....||::
  Fly     3 LYNMSGSPSTRAVMMTAKAVGV--EFNSIQVNTFVGEQLEPWFVKINPQHTIPTLVDNLFVIWET 65

  Fly    69 HAIIGYLVNKYAQSDELYPKDPLKRAVVDQRLHFETGVLFHGIFKQLQRALFKENATEVP--KDR 131
            .||:.|||.:|.:.|.||||||.|:|:::|||:|:.|.|:.||.|.    .|....|..|  ::.
  Fly    66 RAIVVYLVEQYGKDDSLYPKDPQKQALINQRLYFDMGTLYDGIAKY----FFPLLRTGKPGTQEN 126

  Fly   132 LAELKDAYALLEQFLAENPYVAGPQLTIADFSIVATVSTLHLSYCPVDATKYPKLSAWLARISAL 196
            |.:|..|:.||..||....||||.||::||..|:|||||..:  ...|..|:|.:..|......:
  Fly   127 LEKLNAAFDLLNNFLDGQDYVAGNQLSVADIVILATVSTTEM--VDFDLKKFPNVDRWYKNAQKV 189

  Fly   197 -PFYEEDNLR---GARLLADKIRSKL 218
             |.::|:..|   ..:.||:.:..||
  Fly   190 TPGWDENLARIQSAKKFLAENLIEKL 215

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE10	NP_001286570.1	GstA	4..197	CDD:223698	76/195 (39%)
		GST_N_Delta_Epsilon	4..77	CDD:239343	28/72 (39%)
		GST_C_Delta_Epsilon	91..211	CDD:198287	42/125 (34%)
GstD6	NP_524915.1	GST_N_Delta_Epsilon	1..74	CDD:239343	28/72 (39%)
		PLN02395	11..208	CDD:166036	75/204 (37%)
		GST_C_Delta_Epsilon	88..204	CDD:198287	42/121 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45460314
Domainoid	1	1.000	54	1.000	Domainoid score	I4138
eggNOG	1	0.900	-	-		E1_COG0625
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	77	1.000	Inparanoid score	I2398
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1231780at2759
OrthoFinder	1	1.000	-	-		FOG0000035
OrthoInspector	1	1.000	-	-		mtm975
orthoMCL	1	0.900	-	-		OOG6_100130
Panther	1	1.100	-	-	P	PTHR43969
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X30
	11	10.800