DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstE10 and GstD4

DIOPT Version :9

Sequence 1:	NP_001286570.1	Gene:	GstE10 / 37105	FlyBaseID:	FBgn0063499	Length:	240	Species:	Drosophila melanogaster
Sequence 2:	NP_524913.1	Gene:	GstD4 / 48337	FlyBaseID:	FBgn0010040	Length:	215	Species:	Drosophila melanogaster

Alignment Length:	209	Identity:	77/209 - (36%)
Similarity:	113/209 - (54%)	Gaps:	22/209 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 YGTESSPPVRAVLLTLRALQLDHEFHTLDMQAGDHLKPDMLRKNPQHTVPMLEDGESCIWDSHAI 71
            |.:..|...|.:::..:||.|:.....|.:..|:||||:.|:.|||||:|.|.|....||:|.||
  Fly     4 YYSPRSSGSRTIIMVAKALGLELNKKQLRITEGEHLKPEFLKLNPQHTIPTLVDNGFAIWESRAI 68

  Fly    72 IGYLVNKYAQSDELYPKDPLKRAVVDQRLHFETGVLFHGIFK---------QLQRALFKENATEV 127
            ..|||.||.:.|.|:|.||.|||:::|||:|:.|.|.....|         ||..|   ||..:|
  Fly    69 AVYLVEKYGKDDSLFPNDPQKRALINQRLYFDMGTLHDSFMKYYYPFIRTGQLGNA---ENYKKV 130

  Fly   128 PKDRLAELKDAYALLEQFLAENPYVAGPQLTIADFSIVATVSTLHLSYCPVDATKYPKLSAWLAR 192
                    :.|:..|:.||....||||.|||:||.:|:::|||..:  ...|.:|||.::.|.|.
  Fly   131 --------EAAFEFLDIFLEGQDYVAGSQLTVADIAILSSVSTFEV--VEFDISKYPNVARWYAN 185

  Fly   193 ISALPFYEEDNLRG 206
            ...:....::|.:|
  Fly   186 AKKITPGWDENWKG 199

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE10	NP_001286570.1	GstA	4..197	CDD:223698	75/198 (38%)
		GST_N_Delta_Epsilon	4..77	CDD:239343	28/69 (41%)
		GST_C_Delta_Epsilon	91..211	CDD:198287	41/125 (33%)
GstD4	NP_524913.1	PRK10542	1..184	CDD:182533	74/192 (39%)
		GST_N_Delta_Epsilon	1..74	CDD:239343	28/69 (41%)
		GST_C_Delta_Epsilon	88..204	CDD:198287	41/125 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45460301
Domainoid	1	1.000	54	1.000	Domainoid score	I4138
eggNOG	1	0.900	-	-		E1_COG0625
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	77	1.000	Inparanoid score	I2398
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1231780at2759
OrthoFinder	1	1.000	-	-		FOG0000035
OrthoInspector	1	1.000	-	-		mtm975
orthoMCL	1	0.900	-	-		OOG6_100130
Panther	1	1.100	-	-	P	PTHR43969
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X30
	11	10.800