DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstE10 and Clic4

DIOPT Version :9

Sequence 1:	NP_001286570.1	Gene:	GstE10 / 37105	FlyBaseID:	FBgn0063499	Length:	240	Species:	Drosophila melanogaster
Sequence 2:	NP_038913.1	Gene:	Clic4 / 29876	MGIID:	1352754	Length:	253	Species:	Mus musculus

Alignment Length:	115	Identity:	27/115 - (23%)
Similarity:	44/115 - (38%)	Gaps:	37/115 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   133 AELKDAYALLEQFLAENPYVAGPQLTIADFSIVATVSTLHLSYCPVDATKYP-----------KL 186
            :|:|.....:|:||.|               ::.....|.||      .|:|           |.
Mouse    82 SEVKTDVNKIEEFLEE---------------VLCPPKYLKLS------PKHPESNTAGMDIFAKF 125

  Fly   187 SAWL--ARISALPFYEEDNLRGARLLADKIRSKLPKQFDKLWQKAFEDIK 234
            ||::  :|..|....|...|:..:.|.:.:.|.||.:.|   :.:.||||
Mouse   126 SAYIKNSRPEANEALERGLLKTLQKLDEYLNSPLPDEID---ENSMEDIK 172

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE10	NP_001286570.1	GstA	4..197	CDD:223698	16/76 (21%)
		GST_N_Delta_Epsilon	4..77	CDD:239343
		GST_C_Delta_Epsilon	91..211	CDD:198287	18/90 (20%)
Clic4	NP_038913.1	Required for insertion into the membrane. /evidence=ECO:0000250	2..101		6/33 (18%)
Clic4	NP_038913.1	O-ClC	17..252	CDD:129941	27/115 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167844474
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930