DRSC/TRiP Functional Genomics Resources

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Protein Alignment GstE10 and GSTM2

DIOPT Version :9

Sequence 1:NP_001286570.1 Gene:GstE10 / 37105 FlyBaseID:FBgn0063499 Length:240 Species:Drosophila melanogaster
Sequence 2:NP_000839.1 Gene:GSTM2 / 2946 HGNCID:4634 Length:218 Species:Homo sapiens


Alignment Length:170 Identity:40/170 - (23%)
Similarity:76/170 - (44%) Gaps:23/170 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly    55 VPMLEDGESCIWDSHAIIGYLVNKY---AQSD-ELYPKDPLKRAVVDQRLHFETGVLFHGIFKQL 115
            :|.|.||...|..|:||:.|:..|:   .:|: |...:|.|:...:|.|:             ||
Human    60 LPYLIDGTHKITQSNAILRYIARKHNLCGESEKEQIREDILENQFMDSRM-------------QL 111

  Fly   116 QRALFKENATEVPKDRLAELKDAYALLEQFLAENPYVAGPQLTIADFSIVATVSTLHLSYCPVDA 180
            .:..:..:..::..:.|..|.:...|..|||.:.|:..|.::|..|| |...|...:..:.|...
Human   112 AKLCYDPDFEKLKPEYLQALPEMLKLYSQFLGKQPWFLGDKITFVDF-IAYDVLERNQVFEPSCL 175

  Fly   181 TKYPKLSAWLARISALPFYEEDN--LRGARLLADKIRSKL 218
            ..:|.|..:::|...|   |:.:  ::.:|.|...:.:|:
Human   176 DAFPNLKDFISRFEGL---EKISAYMKSSRFLPRPVFTKM 212

Known Domains:


Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.

GeneSequenceDomainRegion External IDIdentity
GstE10NP_001286570.1 GstA 4..197 CDD:223698 35/145 (24%)
GST_N_Delta_Epsilon 4..77 CDD:239343 9/21 (43%)
GST_C_Delta_Epsilon 91..211 CDD:198287 25/121 (21%)
GSTM2NP_000839.1 GST_N_Mu 3..84 CDD:239373 9/23 (39%)
Glutathione binding. /evidence=ECO:0000269|PubMed:16549767, ECO:0000269|PubMed:19808963 7..8
Glutathione binding. /evidence=ECO:0000269|PubMed:16549767, ECO:0000269|PubMed:19808963 43..46
Glutathione binding. /evidence=ECO:0000269|PubMed:16549767, ECO:0000269|PubMed:19808963 59..60 40/170 (24%)