Protein Alignment GstE10 and GSTA4

DIOPT Version :10

• Sequence 1: NP_611322.1
• Gene: GstE10 / 37105
• FlyBaseID: FBgn0063499
• Length: 240
• Species: Drosophila melanogaster
• Sequence 2: NP_001503.1
• Gene: GSTA4 / 2941
• HGNCID: 4629
• Length: 222
• Species: Homo sapiens
• Alignment Length: 203
• Identity: 43/203 - (21%)
• Similarity: 83/203 - (40%)
• Gaps: 61/203 - (30%)

  Fly    19 LLTLRALQLDHEF-----HTLDMQAGDHLKPDMLRKNPQHTVPMLE-DGESCIWDSHAIIGYLVN 77
            :|....::.|.||     ....:|.|:||   :.::     |||:| ||...: .:.:|:.|:.:
Human    22 VLAAAGVEFDEEFLETKEQLYKLQDGNHL---LFQQ-----VPMVEIDGMKLV-QTRSILHYIAD 77

  Fly    78 KYAQSDELYPKDPLKRAVVDQRLHFETGVL----FHGIFKQLQRALFKENATEVPKDRLAELKDA 138
            |:    .|:.|:..:|.::|..:.....:|    .|...|              |.|:..|:.:.
Human    78 KH----NLFGKNLKERTLIDMYVEGTLDLLELLIMHPFLK--------------PDDQQKEVVNM 124

  Fly   139 --------YALLEQFLAEN--PYVAGPQLTIADFSIVATVSTLHLSYCPVDATKYPKLSAWLARI 193
                    :.:.|:.|..:  .::.|.||::||..::.|:..|.        .|.|.:      :
Human   125 AQKAIIRYFPVFEKILRGHGQSFLVGNQLSLADVILLQTILALE--------EKIPNI------L 175

  Fly   194 SALPFYEE 201
            ||.||.:|
Human   176 SAFPFLQE 183

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GstE10	NP_611322.1	GST_N_Delta_Epsilon	4..77	CDD:239343	16/63 (25%)
		GST_C_Delta_Epsilon	91..211	CDD:198287	24/125 (19%)
GSTA4	NP_001503.1	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold	4..82	CDD:469754	17/72 (24%)
		GST_C_Alpha	86..220	CDD:198317	24/126 (19%)