DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstE10 and gst2

DIOPT Version :9

Sequence 1:	NP_001286570.1	Gene:	GstE10 / 37105	FlyBaseID:	FBgn0063499	Length:	240	Species:	Drosophila melanogaster
Sequence 2:	NP_588517.1	Gene:	gst2 / 2539601	PomBaseID:	SPCC965.07c	Length:	230	Species:	Schizosaccharomyces pombe

Alignment Length:	238	Identity:	65/238 - (27%)
Similarity:	92/238 - (38%)	Gaps:	65/238 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MANLILYGTESSPPVRAVLLTLRALQLDHEFHTLDMQAGDHLKPDMLRKNPQHTVPMLED---GE 62
            ||:..||.....|....|:|.|:.|.|.:|....|.|.|:....:.|..||...||.|.|   .:
pombe     1 MAHFTLYSHAGGPNPWKVVLALKELNLSYEQIFYDFQKGEQKCKEHLALNPNGRVPTLVDHKNND 65

  Fly    63 SCIWDSHAIIGYLVNKYAQSD---ELYPKDPLKRAVVDQRLHFET---GVL---------FHGIF 112
            ..||:|.||:.||.:|| .:|   .|...||....:: |.|.|:.   ||:         ||
pombe    66 YTIWESDAILIYLADKY-DTDRKISLSFDDPEYYKLI-QYLFFQASGQGVIWGQAGWFNFFH--- 125

  Fly   113 KQLQRALFKENATEVPKDRLAELKDAYALLEQFLAENPYVAGPQLTIADFSIVATVSTLHLSYCP 177
                   .:...:.|.:.| .|:|....:||..|.:..|:...:.||||           ||:.|
pombe   126 -------HEPVVSAVTRYR-NEIKRVLGVLEDILKDRDYLVANKYTIAD-----------LSFIP 171

  Fly   178 ----------------------VDATK-YPKLSAWLARISALP 197
                                  :|..| :||..||..|:.|.|
pombe   172 WNYNLGGLFGEGKFSFKEEVPQLDFEKEFPKAYAWNQRLLARP 214

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE10	NP_001286570.1	GstA	4..197	CDD:223698	62/233 (27%)
		GST_N_Delta_Epsilon	4..77	CDD:239343	26/75 (35%)
		GST_C_Delta_Epsilon	91..211	CDD:198287	31/142 (22%)
gst2	NP_588517.1	GST_N_Ure2p_like	4..84	CDD:239346	28/80 (35%)
		GstA	5..226	CDD:223698	63/234 (27%)
		GST_C_Ure2p	96..219	CDD:198326	31/142 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	80	1.000	Inparanoid score	I1854
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000035
OrthoInspector	1	1.000	-	-		mtm9258
orthoMCL	1	0.900	-	-		OOG6_100130
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X30
TreeFam	0	0.000	Not matched by this tool.
	8	7.760